Avid Bioservices Inc (CDMO)

[Protector]

PPHM New Trademark: EnAbL

source

Research and development services performed for others in the fields of pharmaceutical, medicinal and drug products; namely, research and development services performed for others and research under contract in the fields of antibody libraries, phages, phage display, identifying candidate therapeutic antibodies and manufacture of therapeutic antibodies

It was filed in AUG 2017. Didn't see it before and the status says: New Application - Record Initialized Not Assigned To Examiner

Normally on or about NOV 4th it should have been assigned an examiner (at which point it becomes at least visible to the public).

Clearly for the AVID service platform that PPHM said was ready to offer to customers.

Other cargos

With the exception of proteins and miRNAs, several bio-active molecules such as phosphatidyl-serine (PS), DNAs, glycans, and glycoprotein [44], have been reported to play an important role in exosome internalization, signal recognition, and novel vaccines. Early evidence suggests that uptake of OvCa derived-exosomes by NK cells requires PS at the exosomal surface, but the presence of PS is not sufficient [8].

The latest study by Jayanthi Lea et al. also provides proof of concept data supporting the high diagnostic power of PS detection in the blood of women with suspected ovarian malignancies [45]. Exosomes were found to contain complex glycans of the di-, tri-, and tetraantennary type with or without proximal fucose, as well as high levels of mannose glycans.

The sialoglycoprotein galectin-3-binding protein (LGALS3BP) was found to be strongly enriched in exosomes, making it a potential marker for exosomes [46]. Scientist have highlighted the translational value of exosomal DNA (exoDNA) in tumour-derived exosomes due to its potential usefulness as a circulating biomarker for the early detection of cancer and metastasis. ExoDNA represents the entire genome and reflects the mutational status of parental tumour cells providing the following advantages: (i) its protection, and, thus inherent stability within exosomes [47], (ii) enriched tumour-derived exosomes found in complex plasma samples [16, 48].

source: via hutschi

AIMO