One patient had a CR (ongoing). He was 68 with mets to one lung (bulky), LN and soft tissue. Prior therapy with 4 doses of Nivo + Urelumab (anti-4-1BB) which failed http://www.iderapharma.com/wp-content/uploads/2017/09/A-Phase-1-2-Trial-of-Intratumoral-IMO-2125-IMO-in-Combination-with-Checkpoint-Inhibitors-CPI-in-PD-L1-refractory-Melanoma.pdf