Think about this: The current Prurisol trial will have at least 108 subjects taking Prurisol twice per day (at least 81 taking 150 mg twice per day and at least 27 taking 200 mg twice per day) at least 81 subjects will be taking a placebo twice per day.
See below, since 55% of subjects taking 100 mg twice per day and strictly adhering to the protocol achieved “clear” (0) or “almost clear” (1) in IGA, and since at least 108 subjects will be taking at least 150 mg twice per day, what percentage of the subjects in the current Phase 2b trial will achieved “clear” (0) or “almost clear” (1) in IGA? 82%
In the previous Prurisol trial
(200 mg group)
At Week 12: 42.8% subjects (ITT) [and 55.0% subjects (PP)] achieved “clear” (0) or “almost clear” (1) in IGA