Vascular Biogenics Ltd (VBLT): With CAR-T, patients that get fevers are...

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Re: wcopeland post# 1144

Tuesday, 08/22/2017 1:15:46 PM

Tuesday, August 22, 2017 1:15:46 PM

With CAR-T, patients that get fevers are considered "lucky" because that means the treatment is working. They usually let the fever, which can reach over 110 F, run the course to the point where the patient is in a coma-like state.

Interestingly, they also give patients acetaminophen when there is a fever because "(a)cetaminophen is used for comfort but does not usually relieve the fever." This aligns with what I said earlier: acetaminophen is an analgesic.

So I don't think it is an issue that VBL is giving patients acetaminophen when they are feverish.

Reference:
https://voice.ons.org/news-and-views/nursing-considerations-for-adverse-events-from-car-t-cell-therapy

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