the pattern is whatever the industry is headed to all of a sudden Bavi is there first MOA for Bavi the same as anti VEGF and vascular inhibition bavi only then Bavi as chemo adjunct then Bavi with checkpoint inhibitors now Bavi with exosomes ( a developing but unproven field) check out the first 3 results 3 complete failures what do you think will happen to the exosome work? heck I may have even missed an MOA or two throw in the Bavi image project and Cotara and you have a bunch of zeros. Now maybe spending less on R and D will be a good thing but it basically means PPHM is shut down. Wait until the Ronin folks take over and start looking at what really has been going on over there.