>My question is whether a clinical center is allowed to do such experiments without an officially accepted protocol (by the EMEA) or whether existing approvals for plasma ATiii indications allow these experiments, because they are very similar to what has been done.<
The former—i.e. this is an off-label use of AT.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”