cjgaddy, thanks and important non-PPHM source that confirms that : A) Avid II up-scale (that are our 2x2000L reactors) will be the PRIMARY source for Roche's will be the rHuPH20 production. B) That it will be ready in Q2/2017 (that is about now and next month) C) That Roche's demand is so high that they will deplete the existing inventory (their...Avid's) D) That PPHM is taking over business from other (the previous primary source...possibly Cook) manufacturers with it 2+6 award winning facilities. And all that supports the SUSTAINED PROFITABILITY claim in about 12 months for PPHM.