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Re: biopharm post# 294014

Wednesday, 04/05/2017 6:49:27 PM

Wednesday, April 05, 2017 6:49:27 PM

Post# of 347009

Janne Pasi



Looks like Janne Pasi working with AstraZeneca and we shall see where these puzzle pieces lead....

"...Combination Chemotherapy

Most recently, Dr. Janne and collaborators at 67 medical centers and clinics in 12 countries have reported some success with a compound of the standard chemotherapy agent Docetaxel in combination with Selumetinib, a drug manufactured by AstraZeneca. The drugs are combined for the treatment of advanced-stage non-small cell lung cancer in patients whose tumors carry a mutation in the gene KRAS. These tumors account for about 20 percent of NSCLC cases, but, so far, no targeted therapy has proved effective against them.

According to Dr. Janne, the clinical trial demonstrated that “a combination of chemotherapy and Selumetinib is significantly better than chemotherapy alone for this group of patients – better in terms of tumor response to therapy and in terms of survival times prior to advance of the disease. It suggests that for the first time we may have an effective treatment for KRAS-mutant lung cancer, which is the largest single subtype of the disease.”
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https://www.asbestos.com/treatment/doctors/pasi-a-janne.php

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Hmmmm....who knows where these pieces lead, especially when Merck is in the race to ....and Jimmy Carter ....hmmm

""I suspect the findings were significant enough that this will be a practice-changing finding," Dr. Pasi Janne, lung cancer specialist at Harvard Medical School and the Dana-Farber Cancer Institute, told NBC News."

https://www.google.com/amp/www.nbcnews.com/health/cancer/amp/lung-cancer-trial-stopped-after-jimmy-carter-drug-stops-tumors-n593726
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