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genisi

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genisi

Re: DewDiligence post# 210062

Thursday, 03/23/2017 4:35:51 PM

Thursday, March 23, 2017 4:35:51 PM

Post# of 251661
I-O MoAs

To put in a bit more scientific way: anti-CTLA-4 works in early-phase T-cell response (priming phase in the lymph nodes) and anti-PD-(L)1 affects the later stages of T-cell immune response (at the effector phase in the lymph nodes and tumor microenvironment).
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