RVNC—Patient self-assessment is a normal efficacy metric for a double-blind trial in a cosmetic indication.
In the phase-3 efficacy trials of RT002 for glabellar lines, RNVC us using the Patient Frown Wrinkle Severity (PFWS) assessment as a component of the primary endpoint (#msg-127061619, #msg-123880628), so it's good to know that the poster presentation at AAD was supportive of PFWS.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”