Monday, February 27, 2017 10:30:33 AM
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"The problem with Neurotrope is that is doesn't address the cause of Alzeimers, ...."
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I strongly suggest that you view (or review) the following presentation.
https://www.veracast.com/webcasts/bio/ceoinvestor2017/18111483071.cfm?0.593469021981
They weren't even targeting plaques, their removal was an unexpected result. Perhaps this approach will reveal the " missing link" behind the root causes of A-beta and Tau that is truly the correct upstream target.
"Neurotrope Bioscience’s lead Alzheimer’s drug candidate, bryostatin, promotes the formation of new synapses in the brains of mice, according to the study, “PKC epsilon Promotes Synaptogenesis through Membrane accumulation of the Postsynaptic Density Protein PSD-95,” recently published in the Journal of Biological Chemistry."
https://alzheimersnewstoday.com/2016/07/05/neurotrope-announces-new-study-published-journal-biological-chemistry-shows-bryostatin-pkc-epsilon-activator-generates-new-synapses-accumulation-synaptic-anch/
"The problem with Neurotrope is that is doesn't address the cause of Alzeimers, ...."
---------------
I strongly suggest that you view (or review) the following presentation.
https://www.veracast.com/webcasts/bio/ceoinvestor2017/18111483071.cfm?0.593469021981
They weren't even targeting plaques, their removal was an unexpected result. Perhaps this approach will reveal the " missing link" behind the root causes of A-beta and Tau that is truly the correct upstream target.
"Neurotrope Bioscience’s lead Alzheimer’s drug candidate, bryostatin, promotes the formation of new synapses in the brains of mice, according to the study, “PKC epsilon Promotes Synaptogenesis through Membrane accumulation of the Postsynaptic Density Protein PSD-95,” recently published in the Journal of Biological Chemistry."
https://alzheimersnewstoday.com/2016/07/05/neurotrope-announces-new-study-published-journal-biological-chemistry-shows-bryostatin-pkc-epsilon-activator-generates-new-synapses-accumulation-synaptic-anch/
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