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Re: DewDiligence post# 185756

Wednesday, 02/22/2017 10:19:05 AM

Wednesday, February 22, 2017 10:19:05 AM

Post# of 257431
ARGS -68% on RCC phase-3 termination for futility:

http://finance.yahoo.com/news/independent-data-monitoring-committee-recommends-130000702.html

Argos Therapeutics Inc., an immuno-oncology company focused on the development and commercialization of individualized immunotherapies based on the Arcelis precision immunotherapy technology platform, today announced that the Independent Data Monitoring Committee (IDMC) for the company’s pivotal Phase 3 ADAPT clinical trial of rocapuldencel-T in combination with sunitinib/standard-of-care for the treatment of metastatic renal cell carcinoma (mRCC) has recommended that the study be discontinued for futility based on its planned interim data analysis. The IDMC concluded that the study was unlikely to demonstrate a statistically significant improvement in overall survival in the combination treatment arm, utilizing the intent-to-treat population, the primary endpoint of the study.

Caution: ARGS has about $41M in debt, reducing its net cash to <$30M.

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