Biotech Values

[Praveen]

AMD/Aslan,

I am bearish about topical eye drops for AMD and will be until I see some solid efficacy data without SE. My reasons are:

I feel the topical eye drops don't efficiently deliver drugs to the choroid or retina because of factors like

long diffusional path length
counter directional intraocular convection
tearing
corneal impermeability to large molecules

Coz of the corneal barrier and negligible levels in posterior segment,I want to see some solid data b4 I believe in them.

I own some REGN and it has shown early promising data. Any comments on the Regeneron's drug?

Regards,
Praveen