Biotech Values

[DewDiligence]

MNTA, CSL ink partnership for Fc programs:

http://ir.momentapharma.com/releasedetail.cfm?ReleaseID=1006767

Momenta and CSL Announce Collaboration and License Agreement to Develop Fc Multimer Programs, Including M230, a Selective Immunomodulator of Fc Receptors

Momenta Pharmaceuticals, Inc. (Nasdaq:MNTA) and CSL Limited (ASX:CSL) today announced that they have entered into an exclusive research collaboration and worldwide license agreement to develop and commercialize Fc multimer proteins, including Momenta's M230, a selective immunomodulator of Fc receptors, which is expected to enter the clinic in 2017.

…"This collaboration and license agreement with CSL validates our belief that M230 is an exciting recombinant product candidate for potential use in autoimmune indications. It was developed using our proprietary Fc biology platform and understanding of how intravenous immunoglobulin (IVIg) works in autoimmune diseases," said Craig A. Wheeler, President and Chief Executive Officer of Momenta Pharmaceuticals. "As the global leader in immunoglobulin (Ig) therapy, CSL is the ideal development and commercialization partner for us in the area of Fc biology given their expertise in developing plasma-derived medicines and focus on creating disruptive recombinant products in the autoimmune space."

"We are delighted to announce this collaboration with Momenta, who are leaders in the Fc biology space," said Paul Perreault, CEO and Managing Director, CSL. "M230 is a very exciting prospect and offers CSL the potential to further grow and expand our long-term global leadership in helping those patients with autoimmune diseases that are treated with immunoglobulins."

Under the terms of the agreement, Momenta will grant CSL an exclusive, worldwide license to Momenta's intellectual property relating to M230. Momenta will receive a $50 million upfront license fee payment from CSL and will also be eligible for up to $550 million in contingent clinical, regulatory and commercialization milestone payments. Momenta has the option to elect a cost and profit-sharing arrangement, for which Momenta would fund a proportion of global development and commercialization costs in exchange for a share of U.S. profits, and milestones and royalties outside the United States. Momenta has the option to enter into an agreement to co-promote M230 and any other collaboration product in the U.S.

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