ENTA starts phase-1 trial of NASH compound, EDP-305: http://finance.yahoo.com/news/enanta-pharmaceuticals-initiates-phase-1-201200159.html EDP-305 is an FXR agonist—the same drug class as ICPT's OCA and GILD's GS-9674 (acquired from PFNX in 2015: #msg-109653984). ENTA has asserted that EDP-305 is substantially more potent than ICPT's OCA—see slides 24, 26, &27 at http://jpmorgan.metameetings.com/confbook/healthcare16/stash/slides/19782/confbook_slideshow.php .