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Re: entdoc post# 273032

Wednesday, 09/21/2016 4:33:53 PM

Wednesday, September 21, 2016 4:33:53 PM

Post# of 346052
Hello Ent, re your post excerpted in relevant part below:

We see statistically significant differences in many instances that do not translate into a cost-effect significant improvement in quality of life. In other words, OS might be extended from 6 months to 8 months, which might attain statistical significance, but is not a marketable difference in treatment.



Remember we agree on your issue re treating advanced lung cancer - but I do have to take serious exception to your statement highlighted above in red - as we've discussed before, we are dealing with incremental improvements to the treatment of all kinds of cancers - and no, they of course do not offer a cure and in most cases not even a truly significant improvement to quality of life - but to say they do not present a "marketable difference in treatment" is quite simply incorrect - the most recent example of course being BMY receiving accelerated approval for NSCLC for just a two month improvement in MOS - so "incremental" is most certainly "marketable."

Enjoy the rest of your day.

James
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