I haven't followed the anti-TNF / sepsis area closely but recall reading that it is not expected to be a dramatic answer to the sepsis problem. I think the contribution of TNF to the condition probably varies between cases and between time points within a particular case.
My interest follows from recent revelations that SCLN's Zadaxin is being used in China for "perioperative infections" , which I think can be safely translated as meaning sepsis , although in the case of Zadaxin I presume it's being given as a prophylactic measure prior to intensive surgical procedures.
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