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Re: mcbio post# 202473

Friday, 07/08/2016 1:36:24 PM

Friday, July 08, 2016 1:36:24 PM

Post# of 257431

You'd be insuring against a safety event that could harm or kill the patient.



Right, and that suggests the applicability of the suicide switch is more a consideration during development of this treatment paradigm.

In other words, I don't think these switches are going to be a *feature* for CAR-T therapy. My bet is they'll turn out to be like training wheels... useful as a commodity tech while companies figure out the CAR-T paradigm, but obsolete long-term.

I think they have meaningful long-term applicability in other areas, so I'm purposefully limiting this viewpoint to CAR-T specifically.

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