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Re: sunstar post# 266853

Thursday, 06/16/2016 5:19:50 PM

Thursday, June 16, 2016 5:19:50 PM

Post# of 347009
sunstar, no actually that troubles me:

"... Patients enrolled were those who had received no prior systemic chemotherapy treatment for their advanced disease and whose tumors expressed high levels of PD-L1 (defined as a tumor proportion score of 50 percent or more)...”



Suppose we change the thinking on this for a moment (and I have suggested this on this board already in 2011 or in 2012).

Assume for a moment that chemo therapy does more harm then good. It destroys healthy cells, causes infections and longer lasting side effects and certainly asks a price of the patient in terms of overall condition and immune vulnerability.

Then running AFTER such damage doesn't seem the best conditions to perform in. So what a luxary to be allowed to run a clinical trial Chemo alone versus I-O alone where there is no chemo in the arm under investigation.

Just think about it! And therefor PPHM MUST run clinical trials Durva+Bavi and NOT Durva+Bavi+Chemo IMO.

Peregrine Pharmaceuticals the Microsoft of Biotechnology! All In My Opinion. I am not advising anything, nor accusing anyone.

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