chenzo, your reply is out of context. I was referring to the provisions PPHM build into the SUNRISE protocol in case the control arm would outperform expectations and in case a new SOC would appear during the SUNRISE trial.
These have been explicitly mentioned and hence this applies:
And my theory is that you do not build a door on the hen-house to keep the fox out and then leave the door continuously open during the night.
Peregrine Pharmaceuticals the Microsoft of Biotechnology! All In My Opinion. I am not advising anything, nor accusing anyone.