I do not own any ENCY but have thought about purchasing after the latest decline. I think they will get the full approval probably after negotiating a post approval phase 4 study. There are other treatments for PAH including viagra. Myogen is hot on the heals of all the current meds but they haven't had there day in FDA hell yet. The reason I held off in purchasing ENCY is that it is unclear to me that the market for PAH collectively for all the products will be billions of dollars (someone correct me if I am wrong).
I have recently bought DSCO another example of two approvable letters from the FDA at an average cost of about $1.90. I believe their product is superior to current available products (the data supports this) and I think they will get the manufacturing right (eventually, hopefully!!).