IMO pphm is going to farm out or partner all later phase trials at least until their manufacturing provides enough revenue to limit dilution. In the meantime they will do phIs and let NCCN and MSK, etc also play with the drug. If they find something they will partner later phases. He'll, they may already have a deal with AZN to do their later phases if AZN drug combos pan out. They might become a early development arm or at least do early development to keep AZN honest and be ready to partner pphm IP with others if AZN balks.