SCIOS, Inc. A biopharmaceutical

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Interesting post from RB About Human Brain Natriuretic Peptides.

http://www.ragingbull.altavista.com/mboard/boards.cgi?board=SCIO&read=134

By: buck45 $$
Reply To: None Wednesday, 27 Sep 2000 at 2:59 PM EDT
Post # of 134


Block Buster United States Patent Issues Yesterday
6,124,430
Mischak , et al.
September 26, 2000


Human brain natriuretic peptides

Abstract

The present invention provides reagents and assays for the quantification of hBNP in biological
fluid samples such as plasma or serum. Antibodies are provided which are monospecific to
epitopes comprising the amino acid sequences 5-13, 1-10 and 15-25 of hBNP. These antibodies,
and peptide fragments containing these sequences, can be employed in the assays of the
invention, which may be carried out in a sandwich format or a competition format.


Inventors:
Mischak; Ronald P. (Palo Alto, CA); Lim; Garrett A. (Havertown, PA);
Scardina; Jan Marian (San Carlos, CA)
Assignee:
Scios Inc. (Sunnyvale, CA)
Appl. No.:
942332
Filed:
October 1, 1997


U.S. Class:
530/324; 436/544; 530/327; 530/839; 530/841
Intern'l Class:
C07K 014/47
Field of Search:
436/544 530/324,327,839,841



(Voluntary Disclosure: Position- Long; ST Rating- Strong Buy; LT Rating- Strong Buy)