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DewDiligence

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DewDiligence

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Re: semi_infinite post# 200667

Thursday, 04/07/2016 4:01:11 PM

Thursday, April 07, 2016 4:01:11 PM

Post# of 252430
In RVNC’s BELMONT study, the 2-point response rate at 28 days was 85% in the RT002 40U arm (the dose being advanced to phase-3) and was 76% in the Botox arm—see slide #17:

http://investors.revance.com/common/download/download.cfm?companyid=AMDA-2GNRV0&fileid=879866&filekey=49C43CF1-9EAE-4E93-9666-420214DA7486&filename=RVNC_Company_Presentation_March_2016.pdf

So, Alphaeon’s 68-70% is low.

Note: It is immaterial whether the response rate is measured at 30 days (in the Alphaeon trials) or at 28 days (in RVNC’s BELMONT study)—both time points should capture the maximum treatment effect.

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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