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Re: DewDiligence post# 198913

Friday, 01/08/2016 8:41:39 PM

Friday, January 08, 2016 8:41:39 PM

Post# of 257375
Diffusion Pharmaceuticals reverse merges into RESX:

http://finance.yahoo.com/news/diffusion-pharmaceuticals-completes-merger-restorgenex-210500865.html

Diffusion Pharmaceuticals LLC, a clinical-stage biotechnology company focused on the development of novel small molecule therapeutics for cancer, today announced the successful completion of its merger with RestorGenex Corporation (RESX). The combined company is changing its name to Diffusion Pharmaceuticals Inc.

…Diffusion is developing its lead drug, trans sodium crocetinate (TSC), for use in the many cancers types in which tumor hypoxia (oxygen deprivation) is known to diminish the effectiveness of current treatment paradigms. TSC targets the cancer’s hypoxic micro-environment, re-oxygenating treatment-resistant tissue and making the cancer cells more susceptible to the therapeutic effects of treatments such as radiation therapy and chemotherapy, without the apparent addition of any serious side effects. TSC has potential application in other indications involving hypoxia, such as stroke and neurodegenerative diseases.

Good luck with that!

A Phase II clinical program, completed in the second quarter of 2015, evaluated 59 patients with newly diagnosed glioblastoma multiforme (GBM). The study demonstrated a favorable safety and efficacy profile for TSC combined with standard of care… A Phase III program in newly diagnosed GBM is expected to commence in 2016. Additional planned studies include a Phase II/III trial in pancreatic cancer, also expected to commence in 2016. A Phase II/III study in brain metastases is also being planned.

A ticker-symbol change will presumably be implemented in due course.

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