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Re: md1225 post# 243040

Wednesday, 11/18/2015 2:54:07 AM

Wednesday, November 18, 2015 2:54:07 AM

Post# of 347009

Opdivo did well in less then twenty percent of patients ie "responders" pd1 positive patients 20 months.


Opdivo was 17 months O/S in the entire population. And with substantially less serious AEs than docetaxol (and by inference, doce+bavi).

That is the target to beat.

I believe we see complete responses in the durvolumab trial when combined with Bavituximab


Very possible. But that will be a long tough road. Using durvo (vs Opdivo) may make running an early stage trial easier, but the entire road to approval becomes more complicated. I seriously doubt this combo is close to approval this decade.
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