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Re: DewDiligence post# 195232

Wednesday, 10/28/2015 10:21:09 AM

Wednesday, October 28, 2015 10:21:09 AM

Post# of 251718
Announced FoB Collaborations

[PFE returns Rituxan/Herceptin rights to Celltrion; PFE’s internal
(i.e. non-HSP) programs for these FoBs are more advanced than
the Celltrion programs originally partnered with HSP.]



Items are shown in reverse chronological order. This table does not purport to be exhaustive.


Date Targets Geography iHub References

AZN-Fujifilm/Kyowa 7/15 Avastin global #msg-115666552
PFE(HSP)-PFNX 2/15 Lucentis global #msg-110725481
Merck KGaA-Hanwha 2/15 Enbrel ex-US #msg-110668714
EPRS-Livzon 9/14 5 mAbs China #msg-106600322
NeuClone-Serum Inst 7/14 10 mAbs global #msg-104136710
Liomont-Oncobiolgcs 6/14 2 mAbs Mexico #msg-103754486
PlantForm-PhrmaPrxs 6/14 Avastin Brazil #msg-103576633
Lupin-Yoshindo 4/14 Enbrel Japan #msg-101018361
EPRS-Ranbaxy 1/14 Remicade Asia/Africa #msg-95745192
BXLT-CHRS 9/13 Enbrel ex-US #msg-91645674
Oncobiolgcs-Huahai 5/13 # global #msg-87734336,#msg-87744882
Strides-Pfenex 4/13 Betaseron global #msg-87014470
MRK-Samsng/BIIB 2/13 @ @ #msg-114478003,#msg-84781042,#msg-69629103
Catalent-UMN 12/12 various Asia #msg-82556713
Merck KGaA-RDY 6/12 oncology global #msg-76359649
Daiichi-CHRS 5/12 Enbrel Asia #msg-75397629
Fujifilm-Kyowa 3/12 Humira unspecified #msg-73800486
AGN-Bioton 2/12 insulin US & Europe #msg-74987123
AGN-AMGN 12/11 † global #msg-70097496,#msg-117190738
BXLT-MNTA 12/11 Humira global #msg-110925786
PFE(HSP)-Celltrion 10/09 z global #msg-84519981
MYL-Biocon 6/09 x global #msg-72421544,#msg-84561737
Procognia-UTR n/a Humira unspecified #msg-84340976

†Herceptin, Avastin, Rituxan, Erbitux; AMGN working independently on Humira and Remicade.

@ Enbrel [worldwide except US/EU/Japan], Remicade [worldwide except EU/Russia/Turkey], Humira [worldwide except EU/Russia/Turkey], Herceptin [worldwide], Lantus [worldwide].

#Humira, Rituxan, Avastin, Herceptin.

x Nine products: Herceptin, Neulasta, Avastin, Humira, Enbrel, Lantus, Novolog, Humalog, one undisclosed.

z Remicade (approved in EU), Enbrel, Erbitux, Synagis, Humira, Avastin; Riruxan and Herceptin returned to Celltrion in 9/15.

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