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Re: DewDiligence post# 30156

Thursday, 06/15/2006 3:59:01 PM

Thursday, June 15, 2006 3:59:01 PM

Post# of 257262
Re : ANDS off 9% on surprise departure by CEO

I wonder if ANDS recent woes , including the departure of the CEO , might be related to recent research showing that TLR7 activation is implicated in lupus. ANA 975 (HCV) and one of their anti-cancer candidates are TLR7 agonists. This links to a recent article posted by PL1 on iHub PPHM.

http://tinyurl.com/o6tfn

A PubMed search on TLR and lupus shows several papers over the past year or so implicating TLRs , in particular TLR7. Of couse ANDS should have the expertise to develop the appropriate antagonists , as well , so maybe the news isn't all bad. wink

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