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biomaven0

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biomaven0

Re: DewDiligence post# 194086

Wednesday, 08/05/2015 12:47:04 PM

Wednesday, August 05, 2015 12:47:04 PM

Post# of 257275
>>n case #2, the DSMB might recommend upsizing the enrollment

I think that would play havoc with the significance analysis. The case you describe is different from an upsizing following a power analysis.

Peter
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