Thanks for sharing your very informative and insightful email to Leo. Although Leo didn't give a direct answer to question #5:
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5) One last one just for fun, some have speculated that a buyout might mean $1.5 billion for CTIX, or $10 a share. Would you accept a $1.5 billion offer at this point?
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Allow me to give my succinct interpretation of Leo's very long answer: Hellllllll no!