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Alias Born 09/05/2002

Re: backstroke_ post# 192609

Tuesday, 06/16/2015 7:40:28 PM

Tuesday, June 16, 2015 7:40:28 PM

Post# of 257286

AAVL—Of all the issues to pop-up out of the trial, safety isn't on my list. Subretinal injection is fine, little to go wrong with skilled personnel carrying out the vitrectomy.

I respect your knowledge of the company’s technology, but I’m not fully convinced that a safety issue can be ruled out. Inasmuch as VA improved (modestly), it seems strained to assert that the increased retinal thickness in the AVA-101 arm was surely a consequence of natural disease progression and not something more sinister. Regards, Dew

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