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Re: iwfal post# 192506

Tuesday, 06/16/2015 6:37:21 AM

Tuesday, June 16, 2015 6:37:21 AM

Post# of 257684
>>decreasing hepcidin may increase infection rate

I suppose that is possible, but at this point it is well established that high hepcidin levels are associated with higher mortality, both in CKD and HIV anemia. Now that is an association, not proof of causation, but it does make your claim that much less likely.

Here are a couple of references:

>Hepcidin-25 in Diabetic Chronic Kidney Disease Is Predictive for Mortality and Progression to End Stage Renal Disease
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404250/


>Elevated Hepcidin Is Part of a Complex Relation That Links Mortality with Iron Homeostasis and Anemia in Men and Women with HIV Infection
http://jn.nutrition.org/content/early/2015/04/22/jn.114.203158.abstract

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