OCRX—I missed this prior point of yours about SoC being pretty effective on its own, so I'll dial back some of my prior concerns on the interim look showing the need to increase the trial size. Just curious, why is the SoC so detested?
Have you ever taken a bowel-cleaning drug prior to a colonoscopy? Well, that’s what the control arm in the STOP-HE trial consists of. It’s an unpleasant experience for patients, and it’s extra work for hospital staff doing stuff like changing bed sheets.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”