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Re: jq1234 post# 189327

Monday, 03/30/2015 3:42:42 PM

Monday, March 30, 2015 3:42:42 PM

Post# of 251652

OCRX—More useful are what is the chance for that to happen, what is the chance of futility, what is the chance of large size increase, what is chance of small to moderate size increase?

Ask and ye shall receive (see next post).

For simplicity, my model has only one case for any upsized enrollment; note that it hasn’t been disclosed whether the SAP gives the DSMB the flexibility to select various enrollment sizes or whether the DSMB has a binary decision to upsize (by a pre-specified number of patients) or not.

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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