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Re: DewDiligence post# 28533

Sunday, 05/14/2006 5:58:37 PM

Sunday, May 14, 2006 5:58:37 PM

Post# of 257262
COLY – the new phase-2 trials in of PF-3512676 in NSCLC are now on clinicaltrials.gov (link c/o TexasDude):

http://tinyurl.com/q49g3

So now we know that the new Tarceva and Alimta trials are in second-line NSCLC—the setting where Tarceva and Alimta are approved treatments—and the new Avastin trial is in non-squamous first-line NSCLC. The Avastin trial is restricted to non-squamous disease because Avastin has shown some troubling side effects in squamous patients.

PFE appears to be leaving no stone unturned in this program.

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