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Re: kcalt post# 28082

Tuesday, 05/02/2006 10:30:02 PM

Tuesday, May 02, 2006 10:30:02 PM

Post# of 257268
> IDIX – Which limit are they using for viral clearance?<

The 600-copy threshold.

>In the EASL data I'm seeing this: At 12 and 16 weeks, 71 percent and 73 percent, respectively, of patients in the 200 mg/day arm reached undetectable virus levels below 600 copies/mL…<

You’re quite right: 71% (not 66%) is the figure that should be compared to the 38-57% historical clearance rate for ifn+ribavirin at 12 weeks that was cited on the CC. Hence, the comparison to ribavirin is even more favorable for NM283. Regards, Dew

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