Ask any Infectious disease doctor what they would prescribe for ABSSSI and it would be vancomycin 9 times out of 10. Daptomycin is non inferior to V and B is non inferior to V. V is the drug of choice currently. Now if B proves to be non inferior to V in a single dose or even 2 day dosing, B becomes the drug to go to for several reasons. 1. one day dose or 2 2. equal to V 3. no resistance 4. excellent compliance 5. lower overall cost 6. ease of administration