EXCERPT Perhaps the most exciting approval of all came in August from The Medicines Co. for acute bacterial skin and skin structure infection (ABSSSI) drug Orbactiv. Unlike the prior standard of care, vancomycin, which required seven to 10 days of treatment, Orbactiv is given as a single injection and was shown in clinical trials to be just as effective as vancomycin. It could represent a big improvement in patient quality of care, and may even remove the need for treating these patients in the hospital setting (i.e., it could be administered in an outpatient clinic), removing the possibility of further disease transmission.