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Re: BonelessCat post# 75347

Sunday, 10/26/2014 6:57:34 AM

Sunday, October 26, 2014 6:57:34 AM

Post# of 405218

So, the primary outcome is defined by meeting a standard (lesion area has decreased by =20%) and not in comparison to any other drugs. In fact, for all outcomes, there is no comparison to Dapto or any other drug.



I believe that is incorrect. What good is it to know that a drug met the standard a certain % of the time unless that % can be compared to something? Few drugs work 100% of the time.

If, at 2 days B met the standard 90% of the time...is that good? Well, it certainly is if D met the standard 80% of the time. But it is not so good if D met the standard 100% of the time. What we know at this point, again, is that B and D met the standard a similar ("statistically comparable") % of the time at the primary endpoint of 2-3 days.

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