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Re: WorstLuck post# 182105

Monday, 09/22/2014 5:18:30 PM

Monday, September 22, 2014 5:18:30 PM

Post# of 257269
[ENTA] There are two additional problems with sharing costs and profits, as it relates to the 2-drug combination. Let's assume ENTA chooses this option.


1 - ENTA's marketing partner (ABBV) would achieve much higher margins promoting the 3-drug combination to the same group of patients (GT1).

2 - There's a reason why P.I./Interferon-based therapy isn't labeled for GT2/GT3 patients. ABBV/ENTA faces class limitations using protease-based therapy in GT2/GT3 patients. Relying on ribavirin to create a competitive combo is self-defeating due to tolerability issues.










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