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Israeli researchers regenerate torn ligaments and tendons with adult stem cells

By David Brinn April 09, 2006

It's a moment that every athlete fears - when they get the news that they have a career-threatening ligament or tendon tear. And it's not just the pros. Millions of Americans play tennis, jog, or join pickup softball or basketball games every day without proper stretching, resulting in similar injuries.

Over 200,000 Americans undergo tendon or ligament repair each year, usually consisting of tissue grafting and synthetic prostheses, but rarely offering a full pre-injury recovery or a long-term solution. With tendon and ligament injuries presenting a major clinical challenge to orthopedic medicine, Israeli researchers at the Hebrew University of Jerusalem are using adult stem cells to provide new hope for both patients and doctors.

In studies conducted on rats, the researchers at the Skeletal Biotechnology Laboratory at the university's Faculty of Dental Medicine have successfully used adult stem cells to form new tendon or ligament tissue. This novel approach for tendon regeneration was reported in the April issue of the Journal of Clinical Investigation.

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