Biotech Values

[jaybe]

Forgot to update the title, and mislead the entire CML community?

I'd have to give Dr. Cortes more credit than that. I think the answer is found in exclusion criteria #8:

E. Clonal evolution defined as the presence of additional chromosomal abnormalities other than the Ph chromosome has been historically been included as a criterion for accelerated phase. However, patients with clonal evolution as the only criterion of accelerated phase have a significantly better prognosis, and when present at diagnosis may not impact the prognosis at all. Thus, patients with clonal evolution and no other criteria for accelerated phase will be eligible for this study.

Maybe the trial is now limited to chronic phase with documented clonal evolution.