Sunday, April 20, 2014 10:02:36 PM
I didn't really need clarification. Just trying to help others get a firm grip on 22nd's products. Doesn't help anyone on here if people are spreading misinformation.
Post 4640 thanks JB
There is some confusion regarding XXII's Brand B. It is not a low nicotine cigarette. It is considered to be a low tar-to-nicotine cigarette due to it's relatively high nicotine content. It is another product designed to reduce the harmful effects of smoking.
CLARENCE, N.Y.–(BUSINESS WIRE)–22nd Century Group, Inc. (OTCBB: XXII), a company that has developed groundbreaking technology for tobacco harm reduction and smoking cessation products, announced that Dr. Michael Moynihan, Vice President of Research & Development, will present a poster today on the company’s proprietary BRAND B cigarette at the 66th Tobacco Science Research Conference (TSRC) being held in Concord, North Carolina.
Slated for submission to the U.S. Food and Drug Administration (FDA) as a modified risk candidate, BRAND B is reportedly the world’s lowest tar-to-nicotine ratio cigarette. Unlike low tar/low-nicotine brands on the market (previously labeled “light” or “ultra-light” before these descriptors were banned in the U.S. by the Tobacco Control Act in 2010), the nicotine yield of BRAND B is not reduced.
Studies of smokers using low tar-to-nicotine (LTN) research cigarettes such as BRAND B have demonstrated that smoking behavior changes and the dose of smoke inhaled by the smoker including “tar” is significantly reduced (Russell MAH 2000). Specifically, compensatory smoking (e.g., more and/or larger puffs per cigarette) of LTN research cigarettes is greatly curtailed.
Dr. Moynihan’s poster, Effect of Smoking Low Tar-to-Nicotine Ratio Cigarettes on Smoke Exposure, explains that incorporating tobacco with a higher-than-typical nicotine content, LTN cigarettes can be made with lower yields of harmful and potentially harmful smoke constituents while maintaining nicotine yields per cigarette similar to popular full-flavor brands. As announced in April 2012, utilizing studies of exposure to smoke constituents and consumer perception, 22nd Century will submit a modified risk cigarette application for BRAND B to the FDA. Leading U.S. brands have an average tar-to-nicotine ratio of approximately 13 – meaning that approximately 13 parts “tar” is inhaled for every part nicotine. LTN cigarettes with a tar-to-nicotine ratio of 7 or less have the potential to reduce smoke exposure by 50 percent. If smoke inhalation with LTN cigarettes is reduced by 50 percent on average, confirmed by biomarkers in exposure studies, reduced harm is expected. 22nd Century’s CEO, Joseph Pandolfino explained, “A cigarette that reduces smoke exposure by an average of 50 percent is effectively a hybrid of a zero-tar e-cigarette and a Marlboro® Gold. How much would smoking- related disease decrease in the U.S. if all the cumulative smoke inhaled by smokers were cut in half?”
Separately, one of the original proponents of LTN cigarettes, Dr. Gio Batta Gori, Director of the Health Policy Center in Bethesda, Maryland, will present a keynote address at 22nd Century Group’s annual shareholder meeting at 2:00 pm on Thursday, September 20, 2012. To be held in Clarence, New York, the annual meeting will be open to company shareholders, select guests, and the media. Dr. Gori will speak on the compelling reasons for less harmful cigarettes and their likely significance to the cigarette industry and the entire tobacco economy.
Dr. Gori is also author of Virtually Safe Cigarettes: Reviving an Opportunity Once Tragically Rejected and a contributor to national research and prevention agendas at the U.S. National Cancer Institute, where he was deputy director of the Division of Cancer Cause and Prevention and director of the Smoking and Health Program. The latter aimed at developing reduced risk cigarettes, an effort for which Dr. Gori received the Superior Service Award of the U.S. Public Health Service.
Recent XXII News
- 22nd Century Group (Nasdaq: XXII) Launches Pinnacle VLN® Trial in California, Opening Another Major New State for Reduced-Nicotine Cigarettes • GlobeNewswire Inc. • 05/21/2026 11:00:00 AM
- 22nd Century Group (Nasdaq: XXII) Expands High-Margin Pinnacle Platform With Launch of Pinnacle Pure at Major U.S. Retailers • GlobeNewswire Inc. • 05/18/2026 01:00:00 PM
- 22nd Century Group (Nasdaq: XXII) Ignites Major VLN® Retail Expansion in Metro New York and Northern New Jersey Under Pinnacle Brand • GlobeNewswire Inc. • 05/15/2026 12:37:00 PM
- 22nd Century Group, Inc. Highlights FDA Filing of VLN® MRTP Renewal Applications for Scientific Review • GlobeNewswire Inc. • 05/12/2026 05:50:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/07/2026 10:30:40 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/07/2026 10:06:10 AM
- 22nd Century Group Reports First Quarter 2026 Financial Results • GlobeNewswire Inc. • 05/07/2026 10:00:00 AM
- 22nd Century Group to Announce First Quarter 2026 Results on May 7, 2026 • GlobeNewswire Inc. • 05/04/2026 01:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/01/2026 09:20:20 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 05/01/2026 09:15:15 PM
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- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 04/13/2026 04:15:24 AM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 04/10/2026 08:35:13 PM
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- 22nd Century Advances Reduced Nicotine Product to Target Approximately Half of the ~$82 Billion U.S. Cigarette Market with 100mm VLN® Product Initiative • GlobeNewswire Inc. • 04/07/2026 12:00:00 PM
- Form S-3 - Registration statement under Securities Act of 1933 • Edgar (US Regulatory) • 03/31/2026 09:00:54 PM
- Form S-8 - Securities to be offered to employees in employee benefit plans • Edgar (US Regulatory) • 03/27/2026 08:30:40 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/26/2026 12:02:51 PM
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- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 03/24/2026 05:57:09 PM
- 22nd Century Group to Announce Fourth Quarter and Full Year 2025 Results on March 26, 2026 • GlobeNewswire Inc. • 03/23/2026 12:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/20/2026 09:14:20 PM
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- Form 8-K - Current report • Edgar (US Regulatory) • 02/20/2026 09:15:28 PM
