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Tony V bailed before the trouble and formed Valdesa, now this. Good businessman, should have followed. The split was after the South America drugs/DMT thing. Lost their way and thought they had it made as the early entrant to the CBD space. He can use the extraction process because it was their shared IP. Magnolia was Big and used the IP too, is now Big for others. Stupidity is the only reason this failed. Trust from shareholders / friends was crushed. Allowing China CBD imports was the killer.
They collaborated way back and are part of the 'Spirit Molecule' thing. $20M MC.?.
Dr. Barker: As of 2013, there had yet to be any examination of pineal glands or their perfusates from any animal species for the presence of DMT. Thus, Dr. Rick Strassman’s hypothesis that DMT was released from the pineal gland had yet to be subjected to true scientific inquiry. However, Rick was aware of the work of Dr. Jimo Borjigin (University of Michigan) who had developed a rat pineal gland perfusion or microdialysis method for examining the release of melatonin as well as other compounds from the pineal in free moving, living animals. Jimo agreed to collaborate on a project to examine these perfusates for DMT and provided me with samples. My laboratory applied the most stringent and sensitive analytical criteria to the analysis, using advanced mass spectrometric methodology, in an effort to determine whether DMT was present in the samples or not. From more than a dozen samples, we found five that, according to the criteria, matched all of the parameters to unequivocally identify DMT as being present in pineal gland perfusates from living rats. I have been doing DMT research since 1976 and, other than data from animals known to be administered DMT, this was my first time to see proof of endogenous DMT in such a biological sample. In fact, it was the first time anyone had seen DMT in such a sample. My reaction to our results? It changed me. The change that occurs in one’s psyche from scientific discovery, especially after a long search, or from proving a hypothesis, whether your own or, in this case, Dr. Strassman’s, is an indescribable and unique physical and emotional experience.
https://dmtquest.org/qa-with-dmt-research-expert-dr-steven-barker/
WOW, held a nickel + with strong volume, guess I'll hold my few shares left for CD and WWH to save the world...GLTA...
Many lost some/most of their gains due to the 'surprise data release' before they (I) could react. I bailed, but will watch and probably be back due to the science and full data and with reasonable expectations.
This is still an effective drug (!!!) but the way the data was handled was pathetic. Just like this White Board turd is.
Consolidation or? Will GEM sell some? Just My Humble Financial Opinions...GLTA...
Still TLD that's being presented, No 'Guest'. Prelim data with a full review to follow after the 60 day data can be evaluated just like the news release and this guy is explaining. NO 'GUEST". Terrible PR value. Terrible presentation. Dude didn't even pre-read the PR it seems. IMO...wtf...
I expect increasing volume for a while...GLTA...
and Yes V, RLF did put out a 'please wait for full data' PR. I'll watch and wait.
https://finance.yahoo.com/news/relief-confirms-release-preliminary-findings-063000961.html
I occasionally look at the counts for 'infections, recovered and deaths'. It seems to show that there are still 50M 'not reported as recovered' out of the 107M infections. Many could be Long haulers with some kind of Lung damage from the after effects from COVID and seem to be an under treated patient group that CM said Ifenprodil may help.
Great idea, IMO...GLTA...
The stage is now set for Buc to show some positive trends in the Clinical Trials. (better? RF-1** data still longer off, if ever).
No hard transfusions courses for limited results like Rem's and other EUA ( or hopeful) drugs' have had for patients.
Early outpatient Treatment is Needed, IMO... Added 25+% more recently...GLTA...
I'll buy back before full data, maybe @$.25. This makes the NRLP deal much more likely...JMHO...GLTA...
Hmmm, maybe NRLP, it makes sense to me, LOL. Both NRX and RLF put Aviptadil on the map and thru the Trial. GEM PIPEs financed it all...GLTA...
I agree but I sent these questions in which may be allowed. Not the best now that I'm actually rereading. Come on folks, write some hard question. Holding Data until after this deal?...GLTA...
""Thank you all for the opportunity to ask questions.
#1. Since your presentation at Sole-Trout there is now the announcement of a BRPA/NRX merger in the works. Moving to Nasdaq is Great news for NRX. How will these moves affect RLF?
#2. RLF has invested strongly in RLF-100. How will the RLF Shareholders be compensated for the Patents covering Formulations of RLF-100 as NRX is using this as a Main Product for NRXP in that Deal?
#3. Together NRX and RLF have put RLF-100 thru the Severe COVID Aviptadil IV Clinical Trial. Now are they partners for an Inhaled 'At Home' product. Can you give Investors more information about these plans?
#4. GEM has been an Investor in NRX for some time to assist NRX with going public and development of NRX-100/101. GEM also has recently provided RLF with more support. How will GEM continue to be involved with NRXP?
Private Investor, GLTA. ""
That started at the Top with Rem/Cloriquin/Steroids/MAbs/ Inhaling Lysol and drinking Clorox.
Many wont take a vaccine. Some refuse simple tasks of respect for others like wearing a Mask in public.
There are a few Treatments targeting different levels of COVID infection that will have their Clinical Trial data publicized in the next few days or weeks... There ARE ACTUAL GOOD TREATMENTS. ARE YOU DIVERSIFIED as a COVID INVESTOR?
I guess my questions about Sole-Trout's IPO work, Patent ownership and partnership, coordinated production and sales could be answered. OK no results but 'when' and 'trending' reviews should be answered. This stuff needs to get moving ASAP, delays are stupid, 'babble time' is way past...GLTA...
Sounds like something Sole-Trout and their "interested Bankers" and GEM could plan. Before or at the same time of Data publication, a Proxy?.
10/1, {$5 @ 320m} - 60M shares from Dec to pacify BRPA rolled into NLXP 1 for 1 . So about 400M shares at IPO. NRXP price set at $10 (NRX deal price)...
International company roots with the Top shelf treatment for Severe Hospitalized COVID and Now "At Home" Patients too, with a portfolio of other Drugs and IP.
5 bagger from there in 30 days. Then?...GLTA...
Interesting link from way back, LOL...
https://r.search.yahoo.com/_ylt=Awr9BNaDKh9g7_IAqQtXNyoA;_ylu=Y29sbwNncTEEcG9zAzMEdnRpZAMEc2VjA3Ny/RV=2/RE=1612684036/RO=10/RU=https%3a%2f%2fmoneymidnight.com%2f2020%2f10%2frelief-therapeutics-otcrlftf-neurorx-to-list-on-nyse-via-merger%2f/RK=2/RS=cOSV5lm3WGAlpQTnOXSx6Lvdw3g-
" Another CT of this drug in IV will have Data next week"
I want to emphasize that GEM is the Major investor of both RLF and NRX. GEM and insiders own a controlling % of RLF shares. NRX is Private still...
GEM wants liquidity at a (much) higher PPS. (IMHFO, LOL). GEM may probably be thinking some (A BIG) Nasdaq Stuff with BIG SPLASHES. Institutional investors/Funds can play too.
THE JEWELS,,, RLF-100 Patent for formulations of VIP and now Inhaler for 'At Home' use.
Then there is NRX-100/101 for PTSD (etc) and ACER-100 for MSUD, both needing commercialization too... Almost sounds like a BP portfolio, IMO...GLTA...
*google GEM/NRX 2019.
Management may not be thinking in smaller terms. Change of Control / Reorg to NASDAQ BONUSERS.
GEM would like a decent return as share structure may change for both their investments, NRX/P and RLF.
The JEWELS are RLF-100 and the 'At Home Inhaler formulations' NOW.
Would strong IP for PTSD and urinary syrup research make this group a SERIOUS Medical company...A BP?...GLTA...
JMHFO, IMWDs,
Crystal Ball Friday w/ 4 Spirits Distillery and Redstickygreen...GLTA... ---------
Sen Bob Dole was a wounded WW2 Hero, hated the Russians, supported personal freedoms and earned Respect from Many. Sad The Republican Party is something very different now...JMHFO...
Elizabeth Dole is carrying on Veteran support work...
https://veteranshomecare.com/?utm_source=microsoft&utm_medium=ppc&utm_campaign=vetassist001&msclkid=c5e94faac48a1ca26dcc2fb7a8ff33af
https://moneymidnight.com/2021/02/rlftf-stock-relief-therapeutics-partner-neurorx-brpa-to-begin-phase-2-3-inhaled-zyesami-covid-19-study/
How about a sticky for the RLF/NRX/BRPA Inhaler news.?.
Yea, their specialty was Retirement homes and care, and they are using the NRXP deal to show in process.
GEM gets 7.5%+ $ of the NRXP deal when it closes and lots of stock.
GEM financed (1.3B, - 37% of OS) RLF for development of RLF-100, Trials and Patent.
GEM wants $$$ for their efforts... NRXP/RLFACER on the NASDAQ, IMO... Money talks, the RLF-100 Patent Rocks, SPAC wont balk.
VANSBIT, SEE THE RLFNRX PR 2-4-21.?.?.
https://moneymidnight.com/2021/02/rlftf-stock-relief-therapeutics-partner-neurorx-brpa-to-begin-phase-2-3-inhaled-zyesami-covid-19-study/
All development costs under the agreement are paid by Relief, providing NeuroRx with non dilutive development capital through drug approval"
Zyesami" Relief also holds a patent issued in the United States and various other countries covering potential formulations of RLF-100TM"
Strait Pot industry products have appeal or repel for some. Sales and production are in work now as compared to development.
Great, but ?
Could Expanding detection to some other Medical needs be targeted? Maybe with the past UF research by Dr Frost.? BlO/BTH paid for all that.
Maybe integrating some 'existing Breathalyzer IP' would bring more eyes here from the Medical communities...and help the sister thru Phase 3.
The capture / detection / analyze hardware and software interfaces are done.?. Program for other Medical related molecules' identification./*
...GLTA...
"We are excited to be the first clinical site for this crucial study, which aims to prevent patients from progressing to respiratory failure and being admitted into the ICU, We have seen the devastation of COVID-19 firsthand and recognize the importance of investigating all potential therapeutics, especially one like ZYESAMI™. Its mechanism holds promise as a treatment for patients in the ICU with Critical COVID-19 and possibly also in the earlier stage of the disease, to reduce disease progression and respiratory failure."
Dr. Richard Lee, Interim Chief of UCI Health’s Division of Pulmonary Diseases and Critical Care Medicine and the Principal Investigator
"The placebo-controlled study is targeted to enroll 144 patients. Once clinical safety is established, NeuroRx will initiate a second outpatient cohort of patients with the aim to determine whether inhaled ZYESAMI™ can be used at home in patients with early stages of COVID-19 and perhaps other viral infections in order to prevent disease progression and hospitalization."
Got to dig through the intros and outros but there are usually nuggets there somewhere.
"Carter at ISAR says no one expects repurposing screens to identify more than a few useful drugs for any particular indication. Even so, she says, “repurposed efforts always need to be deployed when you have the emergence of a new disease, because if there is something that’s readily addressable to the population, you absolutely want to identify it rapidly and take it forward.”
AND
"Although ifenprodil has received considerable interest in its potential neuromodulatory activities in psychiatric conditions, including dependency4 and depression,5 it has also been shown to have an immunomodulatory effect.5,6 In an unbiased screen for compounds capable of reducing cell death induced by infection with the influenza strain H5N1, ifenprodil was found to have a protective effect against H5N1-induced lung damage, in part through its ability to alleviate the H5N1-induced cytokine storm and reduce pulmonary infiltration of neutrophils, natural killer cells, and T cells.6 Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 clinical trial (NCT04382924).7"
Yep, that's what the plans from CM and MW are about, IMO.
Stroke research now joins COVID/SARS/ARDS, IPF, IBD and CKD...GLTA...
Yes, sneeze and Yell into a mask protects others. Those possibly carrying the virus and NOT wearing a mask, asymptomatic, can KILL others. I guess some feel they have that right...
head inverted in re*tum pattern...Read the NEWS, past and present, Real NEWS trumps charts, IMHFO...
I didnt see this posted...
https://moneymidnight.com/2021/02/rlftf-stock-relief-therapeutics-partner-neurorx-brpa-to-begin-phase-2-3-inhaled-zyesami-covid-19-study/
GEM invested in NRX before RLF
https://www.marketscreener.com/news/latest/NeuroRx-Secures-HK-750-Million-Capital-Commitment-From-The-Gem-Group-for-Development-of-NRX-101--29440975/
Probably because unprotected eyes are another route AND the rest of that story is about using the mask to protect Others from me/us. Sneeze / Yell into a mask not the air, Duh...IMO too.
2?
I have used an albuterol inhaler sometimes. I am wondering that if Buc is a potent enough lung medication to be used against COVID why not for other lesser issues of the lungs...GLTA...
3! The Overharvest of all mushrooms is damaging the resource. 10+ cars parked at a local access times a million other places too...JMHFO...
Link please, I feel RLFTF will be at that PPS by 2/26/21. NOT Years, DAYS, IMHFO...
GEM Rules - RLF-100 is their Golden Ticket...
This first one was a great video. Definitely worth the time. There is one from Biopub too...
Part of GEM's moa is Liquidity. Their investments in NRX don't have that but RLF does. RLF has recently received another line of credit from GEM. The tide is raising, not ebbing here, GEM IS paying the bills and should be expected to have a way to pay theirs too until DATA . They may be funding other actions re; NRX and RLF.?.?.
IMO, GEM will control the moves yet RLF will continue to profit and the PPS will remain in this range but with higher VOLUME. GOOD thingee IMHFO...
I wont risk flipping some shares anymore just to keep up with them. GEM's ultimate expectation for RLF now is UP through several possible paths, IMO.
The RLF-100 Patent is the Jewel. FACT...GLTA...
The DSMB has a review set with the company at 210 patients dosed to look at some Data points.(usually not reviewing all data).
The DSMB will determine the "Safety" factor first.
Then they examine "futility" ; if the drug has some effect towards the target " Primary outcomes' listed for the Trial.
The DSMB then allows the Trial to continue or not. This is discussed with the entity sponsoring the Trial.
Releasing that Data before the Trial patients have completed their dosing causes issues with the Trial's "Power".
Excellent news is permission to 'Continue the Trial". This shows "Safety" is OK and there is "NO Futility". IE... It's working'''
JMHO...GLTA...
Sorry 2, part of GEM's moa is Liquidity. Their investments in NRX don't have that but RLF does. RLF has recently received another line of credit from GEM. The tide is raising, not ebbing here, IMHFO...
IMO, GEM will control the moves yet will continue to profit. I wont risk flipping some shares anymore just to keep up with them. GEM's ultimate expectation for RLF now is UP through several possible paths, IMO.
The RLF-100 Patent is the Jewel...GLTA...
In the 'StreetSmart' interview CM was asked if there was a move to DMT because of Ifenprodil concerns, Answer is, "Of course not, this is ADDITIVE and that readout will be later in February".
Good data in some of the outcomes/endpoints will probably involve a lot of work and a lot of planning is probably taking place now. I am betting Dr MW and the CEO are working their teams hard in the areas needed.
Preparing Ifenprodil EUA - {initial marketing - partnerships - production and sales} have all been discussed. DSMB approved to continue to Phase 3 plans.
Also now Phase 1/2 DMT FDA submissions and filings for the 'Rights' of the new DMT intellectual property with the help of Dr Nutt and the other Big names mentioned. Ducks seem to be in a Nice row...
Looks like a FULL plate with GOOD efforts to me...GLTA...
AGN is launching a DMT Trial. No other stock is in this space, maybe it should be included here, IMO...GLTA...
"We dont run the company, we can just Buy-Hold -Sell the stock"
I made my case for a merger and R/S and have not dominated this MB with grinding my opinions into every conversation. YOU TOO can express an opinion and hope for conversations.
As a (wayback) US Veteran I demand access for freedom of speech, but some posters like some politicians abuse these rights. We have heard your input and may or may not agree with it. YOUR Choice is Buy-Sell-Hold. Our choices are the same. I dont 'ignore' posts but... This is a Speculative OTC/F stock.
Your DD has been appreciated but your posting are excessive and disrespectful as has been some replies.
Investors can WAIT or NOT. GEM Rules, IMHFO...GLTY sir...GLTA...E4**...
Wonder Wart Hog, please save us...Maybe the Checkered Demon can help too. We're only down about $.30+ a share average...GLTA...
Elsewhere, I guess. AHHHHHHHHHH...
Looks like no other company has done the needed work to find a viable use for DMT except Dr MW and his team. Great future possible and an open market that needs something.
I dont see the latest Video posted so...
Evidence of human brain and plant neurotoxin co-evolution
The neurotoxin regulation hypothesis proposes that drug use is not novel because human brains and plant neurotoxins coevolved. Genetic evidence suggests that humans have had regular exposure to plant drugs throughout our evolutionary history.[28] Archeological evidence indicates the presence of psychoactive plants and drug use in early hominid species about 2 million years ago.[9] Paleogenetic evidence suggests that the first time human ancestors were exposed and adapted to substantial amount of dietary ethanol, was approximately 10 million years ago.[29] Neurobiological evidence appears to corroborate this story. The fit of allelochemicals within the CNS indicates some coevolutionary activity between mammalian brains and psychoactive plants, meaning they interacted ecologically and therefore responded to one another evolutionarily.[9] This would have only been possible with mammalian CNS exposure to these allelochemicals, therefore to ancient mammalian psychotropic substance use. For example, the mammalian brain has evolved receptor systems for plant substances.
Also an ETF just starting, PSYK...Bored DD...
Psychedelics ETF to launch after sector attracts Thiel's money
Michael Bellusci, Bloomberg News
The world’s first exchange-traded fund for psychedelic-drug companies will debut this week in Toronto, as the investment industry tries to capitalize on rising interest in prospective mental health treatments using the drugs.
The Horizons Psychedelic Stock Index ETF, listed as PSYK, is expected to start trading Wednesday on the NEO Exchange, its operator said. The fund will track the North American Psychedelics Index.
...GLTA...
Receiving data from all the sites and compiling/confirming that data is usually done by the CRO, from what I've read. Then evaluation of that data and applying it to the endpoints of the CT to show statistical significance probably will be done by the Science teams at NRX and RLF.
I/We all want well thought out conclusions. I want those conclusions to be part of a plan for the future...JMO,...GLTA...
Yes we're all impatiently waiting. The company(s) may have further developments re; merger, move to the Nasdaq, partnering further to encompass (all?) the participants that developed RLF-100 and certainly plans about what happens when good data is presented. Some things may still happen before data which are apparently in process right NOW, AlL GOOD, IMO. Things are now down to Possibly HOURS, but maybe a few days still...GLTA...
I'll trust GEM to move correctly and for the Best Returns on their investments. That will Benefit US as a result...
Looks like someone doesn't read the company literature(RVV paperwork) or even the CT. I did..Lots of posts don't equal lots of DD...
He did 'waste time' of his secretary having her answering that D.S. email. Sad, IMHFO.
I can hear him say, 'answer this D.S. email and say...>
""It’s a Phase 3 double blinded study
Do you understand what that is ?
As you see on clinicaltrials.gov the study is progressing well and progressing
Thank you for your support
That’s all that can be said now
Michael Frank""
CEO
DUH...
Dont worry, be Happy. Liberty caps help...GLTA...
BTW, (F)acts (O)ther (P)eople (U)sually (N)ever (K)now... Sp/4***
Shorts declined 80% since mid Dec.
Jan 15, 2021Shares Shorted: 557,624
Net Change: -223,377
Dec 31, 2020Shares Shorted: 781,001
Net Change: -3,308,137
Dec 15, 2020Shares Shorted: 4,089,138