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Monday, 02/01/2021 2:17:59 PM

Monday, February 01, 2021 2:17:59 PM

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Evidence of human brain and plant neurotoxin co-evolution
The neurotoxin regulation hypothesis proposes that drug use is not novel because human brains and plant neurotoxins coevolved. Genetic evidence suggests that humans have had regular exposure to plant drugs throughout our evolutionary history.[28] Archeological evidence indicates the presence of psychoactive plants and drug use in early hominid species about 2 million years ago.[9] Paleogenetic evidence suggests that the first time human ancestors were exposed and adapted to substantial amount of dietary ethanol, was approximately 10 million years ago.[29] Neurobiological evidence appears to corroborate this story. The fit of allelochemicals within the CNS indicates some coevolutionary activity between mammalian brains and psychoactive plants, meaning they interacted ecologically and therefore responded to one another evolutionarily.[9] This would have only been possible with mammalian CNS exposure to these allelochemicals, therefore to ancient mammalian psychotropic substance use. For example, the mammalian brain has evolved receptor systems for plant substances.



Also an ETF just starting, PSYK...Bored DD...

Psychedelics ETF to launch after sector attracts Thiel's money
Michael Bellusci, Bloomberg News

The world’s first exchange-traded fund for psychedelic-drug companies will debut this week in Toronto, as the investment industry tries to capitalize on rising interest in prospective mental health treatments using the drugs.

The Horizons Psychedelic Stock Index ETF, listed as PSYK, is expected to start trading Wednesday on the NEO Exchange, its operator said. The fund will track the North American Psychedelics Index.

...GLTA...