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45,000 shares at 2.94 at 12:53:35
"Although including a placebo group in dose-response studies is desirable, it is not theoretically necessary in all cases; a positive slope, even without a placebo group, provides evidence of a drug effect."
See page 9:
https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM073115.pdf
"Dose-response Concurrent Control (1.3.3)In a randomized, fixed-dose, dose-response trial, subjects are randomized to one of several fixed-dose groups. Subjects may either be placed on their fixed dose initially or be raised to that dosegradually, but the intended comparison is between the groups on their final dose. Dose-response
6trials are usually double-blind. They MAY include a placebo (zero dose) and/or active control. In a concentration-controlled trial, treatment groups are titrated to several fixed-concentrationwindows; this type of trial is conceptually similar to a fixed-dose, dose-response trial. In a regimen-controlled trial subjects are randomized to two or more regimens of the study drug (e.g.,once vs. twice daily, 3 days vs. 7 days)."
https://www.fda.gov/downloads/guidances/ucm073139.pdf
"Although almost all of these patients are given a diagnosis of Alzheimer’s disease, nearly every one of them has a mixture of brain abnormalities."
So that just means that 'almost all of the trial participants' will also have a mixture of brain abnormalities. So if a treatment is found to be effective, that just comes out in the wash.
Second Rett site now recruiting
Locations
United States, Alabama
UAB | The University of Alabama at Birmingham Recruiting
Birmingham, Alabama, United States, 35294
Principal Investigator: Alan Percy, MD
United States, Illinois
Rush University Medical Center Not yet recruiting
Chicago, Illinois, United States, 60612
Principal Investigator: Peter Heydemann, MD
United States, Ohio
Cincinnati Children's Hospital Medical Center Recruiting
Cincinnati, Ohio, United States, 45229
Principal Investigator: Shannon Standridge, DO, MPH
ime Price Volume Market
15:58:16 i 3.06 1 BZX
15:58:01 f 3.08 100 NSX
15:57:57 i 3.06 1 BATY
15:57:49 3.07 400 NDD
15:57:47 i 3.06 2 BATY
15:57:44 3.0715 540 NDD
15:57:28 i 3.06 2 BATY
15:57:03 i 3.06 2 BATY
15:57:00 i 3.08 97 NSX
15:57:00 i 3.08 3 BZX
15:56:48 3.06 100 NDD
15:56:41 3.07 800 NDD
15:56:41 3.07 500 NDD
15:56:39 i 3.06 2 BATY
15:56:24 i 3.08 3 NSX
15:56:15 i 3.06 1 BATY
15:56:15 f 3.08 100 NSX
15:55:57 i 3.06 4 BATY
15:55:18 i 3.06 3 BATY
15:54:42 i 3.06 4 BATY
15:54:30 i 3.06 1 BOS
15:54:25 i 3.06 1 BOS
15:54:09 i 3.06 1 BOS
15:53:52 i 3.06 1 BOS
15:53:49 i 3.06 4 BATY
15:53:43 i 3.06 1 BOS
15:53:38 i 3.06 53 NDD
15:53:38 i 3.06 47 NDD
15:53:35 i 3.06 1 BOS
15:53:22 i 3.06 1 BOS
15:53:19 i 3.06 1 NDD
15:53:03 i 3.06 2 BATY
15:52:59 i 3.06 1 NSX
15:52:44 i 3.06 4 BATY
15:52:11 i 3.06 4 BATY
15:51:27 i 3.0773 15 NDD
15:51:00 i 3.06 4 BATY
15:49:39 3.0696 200 NDD
15:49:38 i 3.06 4 BATY
15:49:05 i 3.06 4 BATY
15:48:25 f 3.08 100 BATY
15:48:06 i 3.06 4 BATY
15:46:55 i 3.06 4 BATY
What's with all the 1, 2, 3, and 4 share trades these last 10 minutes? Nonsense
Breakout to 3.70 if it holds 3.11
The gain in your brain falls mainly on the short's bane
The plunder from down under falls mainly on the refunder
The plunder from down under falls mainly on the wonder
The fame in Spain falls mainly on the acclaim
The bain in Spain falls mainly on the brain
5 weeks, as stated in the PR on Monday:
https://finance.yahoo.com/news/anavex-life-sciences-reaches-50-110000726.html
"ANAVEX®2-73 Phase 2a Alzheimer’s disease study previously demonstrated dose dependent improvement in exploratory endpoint of cognition (MMSE) within 5 weeks."
Will we get PDD results in 2019?
07/09/18: PDD P2 approved
10/30/18: First patient enrolled
03/11/19: 50% enrollment achieved (i.e., 60 patients in 132 days)
With all 18 sites now recruiting, and assuming an exponential increase in the enrollment rate due to the system getting up to speed over the last 4 months and the word about the trial getting out, it can be expected that the remaining 60 patients will be enrolled in less than the next 132 days (~ not later than July 22nd).
14 weeks of dosing beginning no later than July 22nd will be completed no later than October 28th.
That leaves at least 2 months (perhaps 3 or more) in 2019 to analyze and report the results. Not impossible.
from https://www.clinicaltrials.gov/ct2/show/NCT03758924?term=anavex&rank=3#contacts
Contacts
Contact: Walter Kaufmann, MD 844-689-3939 rett@anavex.com
Locations
United States, Alabama
UAB | The University of Alabama at Birmingham Recruiting
Birmingham, Alabama, United States, 35294
Principal Investigator: Alan Percy, MD
United States, Illinois
Rush University Medical Center Not yet recruiting
Chicago, Illinois, United States, 60612
Principal Investigator: Peter Heydemann, MD
United States, Ohio
Cincinnati Children's Hospital Medical Center Not yet recruiting
Cincinnati, Ohio, United States, 45229
Principal Investigator: Shannon Standridge, DO, MPH
There are hefty bonuses attached to enrollment percentage thresholds. The next big catalysts will be the meeting of those thresholds, because that will allow a more accurate calculation/prediction around when the last patient will be enrolled/dosed and when readout can begin.
nasdaq shows
16:18:22 $ 3.07 5
16:18:22 $ 3.07 5
16:18:22 $ 3.07 15
16:18:22 $ 3.10 High 5
16:18:22 $ 3.05 Low 1
If you draw a different line to define the long-term downtrend, I would argue we broke through the downtrend in the first week of February.
That seems like simple logic, but the problem is that it is a quadruple bind, including the Assessor. No one is counting anything. The data is being collected, but it's all blinded. So in your simple logic approach, the responsible journalist would need to survey all trial participants/caregivers, in order to determine that more than half of participants were showing improvement. Hard to see how that would happen. Other than that, nobody else involved in the study is counting. They can't. That's what blinding means.
This is unlikely to happen until the trials are over and the results are unblinded. Unlike the Alzheimers 2A (which was unblinded and had no placebo group), the current trials are designed so that no one can know which arm they have been assigned to (i.e., treatment or placebo). So even if a particular trial subject may appear to be improving in some way, there is no way it can accurately be attributed to 2-73 because there is no way to know if that subject is receiving 2-73 until the trial is over. Maybe the subject who is improving, or their caregiver, may suspect they are receiving 2-73 because of the improvement, but no journalist with integrity would be able to report on it without disclosing that there is no way to know whether it has anything to do with the drug.
PDD https://clinicaltrials.gov/ct2/show/NCT03774459?term=anavex&rank=2
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Rett https://clinicaltrials.gov/ct2/show/NCT03758924?term=anavex&rank=3
Masking: Triple (Participant, Care Provider, Investigator)
Alzheimers 2B/3 https://clinicaltrials.gov/ct2/show/NCT03790709?term=anavex&rank=4
Intervention Model Description: Randomized 1:1:1 to two different ANAVEX2-73 doses or placebo
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Spanish language mention of the PDD trial dated 2/26/19:
https://www.immedicohospitalario.es/noticia/15968/espana-acoge-el-unico-estudio-de-europa-para-pacientes-de-parkinson
Translation:
February 26, 2019 17:56
This is the second phase of the ANAVEX ® 2-73 clinical trial, which has the participation of 20 hospitals throughout the national territory.
Parkinson's disease affects around 300,000 people in Spain and it is estimated that 1 in 3 patients has associated dementia. Dementia associated with Parkinson's disease is characterized by severe alterations in mental functions, including memory, the ability to pay attention, the ability to produce sound judgments and plan the steps necessary to complete a task. Despite the high prevalence of Parkinson's disease with associated dementia, the second phase clinical trial ANAVEX ® 2-73 is the only study currently in the European Union and is taking place in Spain.
"Despite the high frequency of association between Parkinson's disease and cognitive impairment or dementia, treatment options are limited and will be more than 15 years without new pharmacological developments in this field," says Dr. Eric Freire Álvarez , a specialist in neurology at the General University Hospital of Elche and the IMED Elche hospital , and one of the researchers in the Phase II study of ANAVEX ® 2-73 for the treatment of Parkinson's with Dementia. "Parkinson's disease is the second most frequent neurodegenerative disease, after Alzheimer's disease, having a high prevalence in elderly people, but also being present in younger people, and it is expected that it will become a It is important to bear in mind that this is not an exclusively motor disease, since it is also associated with multiple non-motor symptoms, among which are the alterations in the behavior and cognitive deterioration or dementia, " says the doctor.
According to data from the Spanish Society of Neurology, the number of patients with Parkinson's disease will double in the next 20 years and will triple by 2050. This increase in prevalence will occur due to the increase in life expectancy, the development of new diagnostic solutions and therapeutic and due to a greater awareness of this disease of great prevalence in society and that despite requiring an early diagnosis is treatable.
In addition, the dementia associated with Parkinson's disease increases as the disease evolves and represents an important repercussion for the patient's functional capacity and for their family environment, even going so far as to imply a reduction in the life expectancy of these patients.
by IM Médico Publimas Digital sl
It's not a typo, they're just rounding up. The current trial is a phase 2b and a phase 3 running concurrently. Whoever put that spreadsheet together just stated the 3. The same goes for every other company on that list. They're either 1, 2, or 3, no a's or b's and no 2/3's
The Examples in a patent application can be "working examples" or "prophetic examples."
A working example describes results actually obtained and is written in the past tense.
A prophetic example describes results that are anticipated but not yet obtained and is written in the present tense. These are used to obtain an earlier priority date, even though the data/results have not yet been obtained.
The examples in this patent application regarding sleep/seizures/MS are written in the present tense, so they are prophetic examples. Apparently the hope is that the ongoing trials will actually show these results. If they do, the trial data/results can be submitted to the Examiner in the form of a Declaration, to support the earlier submitted prophetic examples.
see MPEP 2164.02 (https://mpep.uspto.gov/RDMS/MPEP/e8r9#/e8r9/d0e215531.html)
see also page 1171 http://law2.wlu.edu/deptimages/law%20review/65-3henry.pdf
Anavex Life Sciences Corp, Inst Holders, 4Q 2018 (AVXL)
1/22/19, 3:48 AM
The following table shows the largest shareholders in ANAVEX LIFE SCIENCES CORP COM (AVXL) for the quarter ended December 31, 2018, listed by holding size. The list represents up to 50 of the largest holders in the company.
Note: Unless otherwise mentioned the reporting date is 12/31/2018
Institution Shares Shares % Last
Held Changed Held Report
Park West Asset Management LLC 3,442,165 500,000 7.389 09/30
The Vanguard Group Inc. 1,647,471 1,647,471 3.536 09/30
Knoll Capital Management LP 724,205 0 1.555 09/30
Millennium Management LLC 569,361 (98,345) 1.222 09/30
Geode Capital Management LLC 288,261 7,156 0.619 09/30
BlackRock Fund Advisors 217,649 103,107 0.467 09/30
Susquehanna Financial Group LL 203,999 203,999 0.438 09/30
Group One Trading LP 120,030 (17,972) 0.258 09/30
Goldman Sachs & Co. LLC (Priva 115,954 115,954 0.249 09/30
Northern Trust Investments In 111,979 111,979 0.240 09/30
SNS Financial Group LLC 70,000 0 0.150 09/30
BlueCrest Capital Management ( 69,985 (100,717) 0.150 09/30
Element Capital Management LLC 67,059 (133,911) 0.144 09/30
Citadel Advisors LLC 65,364 65,364 0.140 09/30
T. Rowe Price Associates Inc. 55,928 271 0.120 09/30
SSgA Funds Management Inc. 55,166 55,166 0.118 09/30
Edmond de Rothschild (Suisse) 50,000 50,000 0.107 09/30
Credit Suisse Securities (USA) 36,507 (849) 0.078 09/30
The Bank of New York Mellon Co 29,858 29,858 0.064 09/30
Brightworth LLC 28,625 0 0.061 09/30
Analytic Investors LLC 25,621 (1,580) 0.055 09/30
PHH Investments Ltd. 20,833 (19,067) 0.045 09/30
AllSquare Wealth Management LL 16,330 0 0.035 09/30
Jump Trading LLC 15,697 15,697 0.034 09/30
Raymond James Financial Servic 15,250 15,250 0.033 09/30
Wells Fargo Bank NA (Private 14,841 14,841 0.032 09/30
Commonwealth Equity Services 14,820 2,000 0.032 09/30
Tower Research Capital LLC 13,367 473 0.029 09/30
Dimensional Fund Advisors LP 10,469 10,469 0.022 09/30
Edge Wealth Management LLC 10,000 0 0.021 12/31
Vanguard Fiduciary Trust Co. 9,668 0 0.021 09/30
UBS Securities LLC 7,623 7,623 0.016 09/30
Wells Fargo Clearing Services 7,300 7,300 0.016 09/30
BlackRock Investment Managemen 7,110 0 0.015 09/30
Simplex Trading LLC 7,026 2,477 0.015 12/31
Morgan Stanley & Co. LLC 6,212 (47,457) 0.013 09/30
Morgan Stanley Smith Barney LL 4,900 4,900 0.011 09/30
CTC myCFO LLC 3,933 0 0.008 09/30
UBS Financial Services Inc. 3,313 (3,000) 0.007 09/30
Advantage Investment Managemen 3,000 0 0.006 09/30
Meeder Asset Management Inc. 2,600 243 0.006 12/31
Securities America Advisors I 2,375 (900) 0.005 09/30
BMO Asset Management Corp. 2,000 2,000 0.004 09/30
KMS Financial Services Inc. 1,750 0 0.004 09/30
Advisory Services Network LLC 1,500 0 0.003 09/30
BNP Paribas Arbitrage SNC 1,310 1,310 0.003 09/30
Bedel Financial Consulting In 1,210 0 0.003 09/30
Citigroup Global Markets Inc. 994 994 0.002 09/30
Cutler Group LP 763 0 0.002 09/30
BDO Wealth Advisors LLC 500 0 0.001 09/30
13F data provided by: Factset Research Systems Inc.;
Please send questions to ownership@factset.com.
Copyright, Factset Research Systems, 2019. All Rights Reserved.
(END) Dow Jones Newswires
01-22-19 0348ET
Hypertension
They should seek approval for stabilizing hypertension and forget about trials for anything else. Off-label scrips can handle every other indication.
I hadn't articulated it that way to myself before, but that's why I'm here.
They could prepare and file that application in 1 day if they wanted to. It'll take years to go through examination at the PTO. If they wanted that application, it's already done.
AVXL Neurology Reviews article
http://www.mdedge.com/neurologyreviews/article/130412/alzheimers-cognition/can-sigma-1-agonist-stabilize-cognition-and
This should draw some interest
I'm holding mine until they are worth $33 a share, like they told me they were worth in May, however long it takes, scam or not.
It's only (alot) of money.
Besides, there are always derivative lawsuits. If it is a scam, it's a blatant one, them pretending to be a real company with real assets, and if it's not a real company with real assets, we'll take his house and car :).
"Lastly, we will release, in complete detail, an "update of operations" and details of new acquisitions in Canada."
They choose not to burden themselves with a self-imposed deadline. Any guesses?
OPEC is holding an "emergency" meeting on Thursday to discuss production cuts.
Do you think our prescient officers might be planning to release the (hype)PR at the absolute best possible time in order to optimally enjoy the fear-driven buying into oil that is undoubtedly going to occur as the impending "emergency" meeting of OPEC approaches? Or do you think they went golfing or perhaps just got hammered last weekend using the money they made in the last 5X run-up, and so just have gotten to it yet?
I don't know what everyone is upset about...he still has 3 hours to meet his own unnecessary and self-imposed deadline. Actually 4 hours if he meant his local central time zone. Plus, don't forget, there are other times zones. He didn't really say which one. Maybe he was referring to a time zone that only occurs at some point in the future, like tomorrow or beyond, making the release only seem to be late to us here in the conventional time zones. Perhaps he is monitoring oil futures, in order to time the release to allow for the least amount of time for investors to consider it before market opens. Maybe he's just waiting for us all to go to bed (don't forget to put out milk and cookies!). It may be better if we just stop posting.
"The company's financial results will be released no later than October 15th, 2006."
Does anyone care to speculate about why he would set a self-imposed, no-later-than deadline to fall on a Sunday? To allow for the release of good results into a down oil market? To allow for the release of bad news when the market is closed?
Good enough reason to release the President's report today?
I've seen it stated on this board that Pinedo stated he would release before 10/15. Anyone know the source of that information?
Anyone care to speculate about the effect that issuing sanctions aginst Iran will have on the price of oil? http://news.bbc.co.uk/1/hi/world/europe/5411694.stm. On the value of domestic sources of oil?
Anyone care to speculate about the effect that a nuclear weapons test by the North Koreans will have on the price of oil? http://news.bbc.co.uk/2/hi/asia-pacific/5412146.stm. On the value of domestic sources of oil?
CollegeStock, Inc.: The Deans List for 9/30 PGPM, FBVG, TAKDF, FDRA, and OTCI
Oct 02, 2006 (M2 PRESSWIRE via COMTEX) -- The Dean's List for September 30,
2006 is: Biotel Inc. (OTC: BTEL), Pilgrim Petroleum Corp. (OTC: PGPM), Fire
Mountain Beverage Company (OTC: FBVG), TransAKT Ltd. (OTC:TAKDF), Foldera Inc.
(OTC: FDRA), and Ortec International, Inc. (OTC: OTCI)
Visit http://www.CollegeStock.com to receive our educational small-cap
newsletter ABSOLUTELY FREE!
The Dean's List for September 30, 2006
Biotel Inc. (OTC: BTEL) http://finance.yahoo.com/q?s=BTEL.OB
On Friday BTEL announced revenues for the year ended June 30, 2006 of
$10,223,000 versus $10,169,000 for the year ended June 30, 2005. Biotel also is
reporting net income of $452,000 for the year ended June 30, 2006 versus net
income $444,000 in the preceding year. For the three months ended June 30, 2006,
Biotel recorded revenues and net income of $2,735,000 and $27,000, respectively,
versus revenues and net income of $2,833,000 and $215,000 for the three months
ended June 30, 2005.
Pilgrim Petroleum Corp. (OTC: PGPM) http://finance.yahoo.com/q?s=PGPM.PK On
Friday PGPM announced the company's projected EPS (Net Earnings / Outstanding
Shares) $102,370,000/358,841,164 of 0.29 based on Pilgrim's Future Net Revenues
estimations. Thus, the resulting EPS multiplied by a sustainable growth rate of
25% and multiplied by the average industry P/E ratio of 14.79 (Reuters),
Pilgrim's intrinsic value or estimated stock value should be worth $1.055 per
share. This assessment doesn't include all of Pilgrim Petroleum properties, only
those in Wichita and Archer counties. We will disclose results next quarter for
the rest of our properties.
Fire Mountain Beverage Company (OTC: FBVG) http://finance.yahoo.com/q?s=FBVG.PK
On Friday FBVG announced that October 2, 2006 is the record date for investors
of record to qualify for the Company's stock dividend. The Pay Date for this
dividend will be 10 days following the record date or October 12, 2006.
TransAKT Ltd. (OTC:TAKDF) http://finance.yahoo.com/q?s=TAKDF.OB
On Friday TAKDF announced that all conditions to close its previously announced
proposed acquisition of Taiwan Halee International Co. Ltd. (HTT) have been met,
and the formal closing in Taiwan is due to occur. HTT is a leading manufacturer
of telecommunications equipment, including specialized VoIP-compatible DECT
phone systems (digital cordless phone systems including 1.8GHz,1.9GHz, 2.4GHz
and 5.8GHz). The Company is the exclusive Taiwanese distributor for Sanyo and
Siemens, a distributor for Panasonic and Sharp and an authorized agent for
Brother and Vito.
Foldera Inc. (OTC: FDRA) http://finance.yahoo.com/q?s=FDRA.OB
On Friday FDRA and The World Technology Network (WTN) announced that Richard
Lusk, CEO and Founder of Foldera, is a finalist for a prestigious World
Technology Award as one of the most innovative members of the world of
technology. The World Technology Awards are to be presented at San Francisco
City Hall on November 3rd, at the close of the 2006 World Technology Summit,
which is being held in association with TIME magazine, CNN, Science magazine,
Dow Chemical Company, and the New York Stock Exchange (NYSE).
Ortec International, Inc. (OTC: OTCI) http://finance.yahoo.com/q?s=OTCI.OB On
Friday OTCI announced that the Company has been notified by the Food and Drug
Administration (FDA) that its HDE Supplement is approvable subject to an
inspection by the FDA of its commercial manufacturing facility. In July 2006
Ortec submitted an HDE Supplement application requesting FDA approval to market
cryopreserved OrCel(R), its lead product, for use in Epidermolysis Bullosa (EB)
patients who suffer from Recessive Dystrophic Epidermolysis Bullosa (RDEB)
undergoing hand reconstruction, a well as to cover donor sites (the area from
where skins was removed from another part of the patient's body) created during
the surgery. RDEB, the most severe form of Epidermolysis Bullosa (EB), is a
devastating congenital skin disorder characterized by painful ulcerations and
widespread, permanent scarring resulting in deformity of the hands and feet
which require repeated surgeries and result in a need for replacement skin, such
as OrCel(R).
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OTCPicks.com Daily Market Movers Digest Stock Alerts, Monday October 2, PGPM, CSSSTF, MRDAF, STXX, RGUS
Oct 02, 2006 (M2 PRESSWIRE via COMTEX) -- Today our stock watch alerts today
include stock alerts for Pilgrim Petroleum Corporation (OTC: PGPM), China
Security & Surveillance Technology, Inc. (OTCBB: CSSTF), Meridian Company, Ltd.
(OTCBB: MRDAF), South Texas Oil Company (OTCBB: STXX), and REGI, U.S., Inc.
(OTCBB: RGUS)
Visit http://www.otcpicks.com to register for our FREE Daily Market Mover's
Digest Newsletter and Stock Alerts
OTC STOCK ALERTS
PILGRIM PETROLEUM CORPORATION (OTC: PGPM) "Up 22.22% at close on Friday"
Detailed Quote: http://www.otcpicks.com/quotes/PGPM.php
Pilgrim Petroleum Corporation (OTC: PGPM) operates as an oil and gas exploration
and development company. It holds crude oil and natural gas properties in Texas
with interests primarily in Morgan fields, Morgan 2 fields, Douglas Mineral
Trust field, Lily Hooks field, Meldon White lease, Lockride lease, and Climax
lease, as well as in Patton and Burnett-EE leases. The company, through its
subsidiary, American Petroleum Corp., provides basic accounting, land
administration, regulatory consulting and reporting, engineering, environmental,
pumping and drilling supervision, and marketing services. Pilgrim Petroleum was
incorporated in 1998. It was formerly known as BNP Petroleum Corporation and
changed its name to Pilgrim Petroleum Corporation in 2005. The company is
headquartered in Irving, Texas.
PGPM News:
September 29 - Pilgrim Petroleum Corporation Announces Future Net Revenue and
EPS
Pilgrim Petroleum Corporation (OTC: PGPM) announced today the company's
projected EPS (Net Earnings / Outstanding Shares) $102,370,000/358,841,164 of
0.29 based on Pilgrim's Future Net Revenues estimations. Thus, the resulting EPS
multiplied by a sustainable growth rate of 25% and multiplied by the average
industry P/E ratio of 14.79 (Reuters), Pilgrim's intrinsic value or estimated
stock value should be worth $1.055 per share. This assessment doesn't include
all of Pilgrim Petroleum properties, only those in Wichita and Archer counties.
We will disclose results next quarter for the rest of our properties.
In its efforts to become a fully reporting company, Pilgrim Petroleum concluded
its initial phase of acreage resource estimation and economic valuation. It will
continue to value and put in line the additional properties recently added to
its asset portfolio, while implementing its ongoing well re-activation program.
Pilgrim Petroleum management is focused on multiple horizons with hydrocarbon
potential and is proud to communicate that the company's combined assets of
marginal wells and potential resources will create additional value to its
current and future shareholders.
Rafael Pinedo, President of Pilgrim Petroleum Corporation, commented, "Pilgrim
Petroleum is growing in a very fast pace with substantial opportunities.
Management is committed to continue our process to be listed in Canada. Pilgrim
Petroleum is looking forward to keeping investors informed of its progress and
success in 2006."
CHINA SECURITY & SURVEILLANCE TECHNOLOGY, INC. (OTCBB: CSSTF) "Up 15.52% at
close on Friday"
Detailed Quote: http://www.otcpicks.com/quotes/CSSTF.php
Based in Shenzhen, China, China Security & Surveillance Technology, Inc. (OTCBB:
CSSTF) manufactures, distributes, installs and maintains security and
surveillance systems through its wholly owned subsidiary, Golden Group
Corporation (Shenzhen) Limited. China Security has a manufacturing facility
located in Shenzhen and a R&D facility which leverages an exclusive
collaboration agreement with Beijing University. In addition, China Security has
built a diversified customer base through its extensive sales and service
network that includes 33 points of presence throughout the PRC.
MERIDAN COMPANY, LTD. (OTCBB: MRDAF) "Up 25.00% at close on Friday"
Detailed Quote: http://www.otcpicks.com/MRDAF.php
Meridian (OTCBB: MRDAF) is an established leader in the research/development,
manufacturing, and sales of integrative medical diagnostic equipment. The
company sells its products and equipment to a wide array of customers in the
global health care industry. The company presently holds a total of 18 worldwide
patents on its technology, and has received FDA, as well as other international
regulatory approvals for many of its products.
Meridian is committed to the ongoing global research and advancement of
integrative medical products that contribute to the better health of humanity.
SOUTH TEXAS OIL COMPANY (OTCBB: STXX) "Up 10.78% at close on Friday"
Detailed Quote: http://www.otcpicks.com/quotes/STXX.php
South Texas Oil Company (OTCBB: STXX) engages in the exploration, development,
and operation of oil and gas properties in the United States. The company has
100% working interest in the properties in the Big Foot and Kyote fields of Frio
and Atascosa Counties. As of December 31, 2005, it had interests in
approximately 135 wells, as well as had approximately 5,243.685 gross acres
under lease. The company, formerly known as Nutek Oil, Inc., was founded in 1998
and changed its name to South Texas Oil Company in 2005. South Texas is based in
Big Foot, Texas.
REGI U.S., INC. (OTCBB: RGUS) "Up 30.59% at close on Friday"
Detailed Quote: http://www.otcpicks.com/quotes/RGUS.php
REGI U.S., Inc. (OTCBB: RGUS) owns the U.S. rights to the Rand Cam(TM) rotary
technology that is used in an engine that is a light weight rotary engine with
only two moving parts: the vanes (up to 12) and the rotor, compared to the 40
moving parts in a simple four-cylinder piston engine. This revolutionary design
makes it possible to produce a total of 24 continuous power impulses per one
rotation that is vibration-free and extremely quiet. The Rand Cam(TM) engine
also has multi-fuel capabilities and is able to operate using fuels including
gasoline, natural gas, hydrogen, propane and diesel. Reg Technologies Inc., the
parent company of REGI U.S., Inc., together with it, is in the process of
testing a Rand Cam(TM) diesel engine for a generator application for hybrid
electric cars and for unmanned aerial applications for the U.S. military.
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