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some huge buys Into QI...149k and 132 k..stock is only .18 ..someone knows something!
see the mm's dropped the price of STEM .10 in one quick move!
mick, future l looks bright for Stem cell research now that we are moving from the dark ages in American history.
great post GGGoooooooooooooo STEM
think STEM will go up tomorrow?
this was the best buying OP I believe I will ever have!
only question I have is how low will this thing go?
will keep an eye on the radar for DRYS
cant believe this stock is 4.75 right now!
loving KERX it's building a stable base of investors
UPDATE 1-Infineon upbeat on chances for Qimonda stake sale
Date : 11/11/2008 @ 8:08AM
Source : TFN
Stock : Qimonda Ag (QI)
Quote : 0.132 -0.0069 (-4.97%) @ 1:43PM
UPDATE 1-Infineon upbeat on chances for Qimonda stake sale
MUNICH, Nov 11 (Reuters) - German chipmaker Infineon is still in
negotiations to sell its stake in its Qimonda memory chip unit and is optimistic
it will come to a conclusion this year, Infineon's chief executive said.
"We believe we have good chances to conclude negotiations," Chief
Executive Peter Bauer said on the sidelines of an industry event in Munich on
Tuesday.
He reiterated he wanted to sell the majority of Infineon's 77 percent
stake by the end of the year and if needed give the rest of the shares to
shareholders.
Worries about Qimonda sent stock in parent Infineon down as much as 8.5
percent on Tuesday. It was down 6.82 percent at 2.46 euros by 1223 GMT.
Bauer declined to comment on concerns that Qimonda could face a collapse
due to an ongoing slump in prices for dynamic random access memory (DRAM) chips,
used mainly in PCs.
However, the CEO said Qimonda and its competitors have been hit hard by
the rapid decline in prices.
"Times are worse than we ever expected," Bauer said.
Infineon has been trying to find a buyer for the stake in Qimonda it owns
after carving out and listing its former memory chip unit in 2006 in the hope of
cutting its exposure to the volatile memory chip market.
Bauer reiterated Qimonda could not expect a cash injection from Infineon.
He also said Infineon was in good condition to make it through the
current crisis.
crable: lotta people are betting the markets are in for more corections. luckily for me, I have plenty of time for this investment
think the other MM's were short?
RKH I hear ya, but as long as this is in the bet interest of STEM let it be!
I bought in at 1.26 and feel for the long term this will be a great stock to own
thanks di4
di4 who do you use for Level 2 service?
sounds good to me...this low market is a 25 year event - it will bounce back
MOMO: is this the bottom?
anyone have a good ideal what price to pay for a entry level into CEGE?
anyone playing KERX tomorrow?
my watch list: read below
RCCH BBDA AIG KERX STEM QI USVE FNIX
this stock trades extremely strange....or am I the only one that feels this way
looking for a new entry level for AIG. Years from now we will all do very well if holding long. learn from me, recently I bought at 1.84 and sold at 1.93 because I did'nt want to hold over nite. Next day the big news hit and the pre-trading was over $3.00!!!! what a wakeup that was.
Thought we would get some action today...I was so close in flipping KERX at the opening. truth be known always trust your instincts. I expect news sometimes on the Trial III results of the new drug KERX is working on, as investors we should all do well.
Caveat Emptor
QI NEWS:
UPDATE 1-Infineon upbeat on chances for Qimonda stake saleBy AFX | 11 Nov 2008 | 08:08 AM ET Text Size MUNICH, Nov 11 (Reuters) - German chipmaker Infineon is still in negotiations to sell its stake in its Qimonda memory chip unit and is optimistic it will come to a conclusion this year, Infineon's chief executive said. "We believe we have good chances to conclude negotiations," Chief Executive Peter Bauer said on the sidelines of an industry event in Munich on Tuesday. He reiterated he wanted to sell the majority of Infineon's 77 percent stake by the end of the year and if needed give the rest of the shares to shareholders. Worries about Qimonda sent stock in parent Infineon down as much as 8.5 percent on Tuesday. It was down 6.82 percent at 2.46 euros by 1223 GMT. Bauer declined to comment on concerns that Qimonda could face a collapse due to an ongoing slump in prices for dynamic random access memory (DRAM) chips, used mainly in PCs. However, the CEO said Qimonda and its competitors have been hit hard by the rapid decline in prices. "Times are worse than we ever expected," Bauer said. Infineon has been trying to find a buyer for the stake in Qimonda it owns after carving out and listing its former memory chip unit in 2006 in the hope of cutting its exposure to the volatile memory chip market. Bauer reiterated Qimonda could not expect a cash injection from Infineon. He also said Infineon was in good condition to make it through the current crisis.
I dont mind at all armani...Taint is on ignore
why Taint...does it turns you on?
nothing like HOT FECES LOL
PRESS RELEASE KERX NEWS
Keryx Biopharmaceuticals' KRX-0401 (Perifosine) Data Selected for Oral Presentation at the 50th Annual Meeting of the American Society of Hematology
Last update: 9:28 a.m. EST Nov. 10, 2008
NEW YORK,, Nov 10, 2008 /PRNewswire-FirstCall via COMTEX/ -- Paul Richardson, MD to present results from Phase 1/2 Clinical Trial of Perifosine in combination with Bortezomib (+/- dexamethasone) on Tuesday, December 9, 2008 at 8:30am
Keryx Biopharmaceuticals, Inc. (KERX:keryx biopharmaceuticals inc com
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12:29pm 11/10/2008
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KERX 0.27, +0.04, +18.0%) today announced that data from its Phase 1/2 clinical trial of KRX-0401 (perifosine) has been selected for oral presentation at the upcoming 50th Annual Meeting of the American Society of Hematology (ASH), to be held in San Francisco from December 5-9, 2008.
The study entitled "Phase I/II Results of a Multicenter Trial of Perifosine (KRX-0401) + Bortezomib in Patients with Relapsed or Relapsed / Refractory Multiple Myeloma Who Were Previously Relapsed from or Refractory to Bortezomib," will be presented on Tuesday, December 9th at 8:30 am PST by Paul Richardson, M.D., Clinical Director of the Jerome Lipper Multiple Myeloma Center at the Dana-Farber Cancer Institute in Boston, MA.
This abstract became available for viewing earlier today on the American Society of Hematology website ( www.hematology.org). There were 76 patients enrolled on study at the time of abstract submission, of which 57 were evaluable for response and are reported on within the abstract. An updated analysis will be presented at the conference. As detailed in the abstract, an overall response rate of 40% was seen in evaluable patients. A similar level of activity was seen in the subset of patients who were bortezomib-refractory. In the study, overall response rate is defined to include all MRs, PRs and CRs.
Paul Richardson, MD commented, "The addition of perifosine to bortezomib, with or without dexamethasone, has proved generally well tolerated and continues to demonstrate encouraging activity with an impressive overall response rate and promising time to progression in these heavily pretreated, relapsed and refractory patients."
In addition to the KRX-0401 abstract which was selected for oral presentation, four abstracts on KRX-0401 were accepted for poster presentation. All of the clinical data to be presented demonstrates the potential efficacy of KRX-0401, both as a single agent and in combination with other approved agents, in the treatment of patients with multiple myeloma and waldenstrom's macroglobulinemia.
"We are encouraged by the safety and efficacy results obtained to date on the combination of KRX-0401 and bortezomib in relapsed and refractory multiple myeloma patients who were all previously treated with bortezomib," said Michael S. Weiss, Chairman and Chief Executive Officer of Keryx Biopharmaceuticals, Inc., who continued "we plan to further evaluate the potential efficacy of KRX-0401 as a treatment for multiple myeloma and related disorders and continue to explore the design of a phase 3 program in multiple myeloma."
Summary of KRX-0401 Data Presentations
ORAL PRESENTATION: TUESDAY, DECEMBER 9th
Abstract 870
Title: Phase I/II Results of a Multicenter Trial of Perifosine (KRX-0401)
+ Bortezomib in Patients with Relapsed or Relapsed / Refractory Multiple
Myeloma Who Were Previously Relapsed from or Refractory to Bortezomib
Session Name: Novel Therapies for Myeloma and Related Disorders Session
(7:00- 9:00 AM)
Presentation Time: 8:30am
Location: Gateway Ballroom 103 - South
Clinical Poster Presentations:
SATURDAY, DECEMBER 6th
Abstract 1010
TITLE: Final Results of a Phase II Trial of the Novel Oral Akt Inhibitor
Perifosine in Relapsed and/or Refractory Waldenstrom Macroglobulinemia
(WM)
Session Name: Biologic Therapies for NHL (Excluding Pre-clinical Models)
Presentation Time: 5:30 PM - 7:30 PM
Location: Moscone Center, Hall A
Poster Board no.: I-115
MONDAY, DECEMBER 8th
Abstract 3691
TITLE: Phase I Results of Perifosine (KRX-0401) in Combination with
Lenalidomide and Dexamethasone in Patients with Relapsed or Refractory
Multiple Myeloma (MM)
Session Name: Myeloma - Therapy, excluding Transplantation Poster III
Presentation Time: 5:30 PM - 7:30 PM
Location: Moscone Center, Hall A
Poster Board no.: III-773
Pre-Clinical Poster Presentations:
MONDAY, DECEMBER 8th
Abstract 3663
TITLE: Combination of Nab-Rapamycin and Perifosine Induces Synergistic
Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in
Multiple Myeloma (MM)
Session Name: Myeloma - Pathophysiology / Preclinical Studies excluding
Therapy Poster III
Presentation Time: 5:30 PM - 7:30 PM
Location: Moscone Center, Hall A
Poster Board no.: III-745
Abstract 1555
TITLE: Phenotypic and Functional Effects of Novel Akt Inhibitor
Perifosine on Immune System
Session Name: Lymphocytes and Lymphocyte Activation Poster I
Presentation Time: 5:30 PM - 7:30 PM
Location: Moscone Center, Hall A
Poster Board no.: I-660
Copies of the above referenced abstracts can be viewed online through the ASH website, www.hematology.org.
KRX-0401 (Perifosine) Mechanism of Action and Profile
KRX-0401 (Perifosine) is a novel, potentially first-in-class, oral anti-cancer agent that modulates Akt and a number of other key signal transduction pathways, including the JNK and MAPK pathways, all of which are pathways associated with programmed cell death, cell growth, cell differentiation and cell survival. The effects of perifosine on Akt are of particular interest because of the importance of this pathway in the development of most cancers, the evidence that it is often activated in tumors that are resistant to other forms of anticancer therapy, and the difficulty encountered thus far in the discovery of drugs that will inhibit this pathway without causing excessive toxicity. High levels of activated Akt (pAkt) are seen frequently in many types of cancer and have been correlated with poor prognosis in patients with soft-tissue sarcoma, gastric, hepatocellular, endometrial, prostate, renal cell, head and neck cancers and hematological malignancies, as well as glioblastoma. The majority of tumors expressing high levels of pAkt were high-grade, advanced stage or had other features associated with poor prognosis. High pAkt is often seen in tumors that are resistant to conventional cancer treatments, including radiotherapy, chemotherapy, endocrine therapy, and especially therapy with some of the newer biologicals.
To date, over 1,700 patients have been treated with KRX-0401 in trials conducted both in the United States and Europe. Its safety profile is distinctly different from that of most cytotoxic agents. It does not appear to cause myelosuppression (depression of the immune system that may lead to life threatening infections), thrombocytopenia (a decrease in platelets that may result in bleeding), skin rash, flu-like symptoms or alopecia (hair loss); all of these toxicities occur frequently with many of the currently available treatments for cancer. The main side effects of perifosine are nausea, vomiting, diarrhea and fatigue, but these are either mild or non-existent in lower doses that have induced tumor regression. Responses have been seen with both daily and weekly regimens. At the doses studied, the daily regimens were better tolerated.
In Phase 1/2 trials, KRX-0401 has induced tumor regressions and/or caused disease stabilization in a variety of tumor types. KRX-0401 has shown single agent partial responses in renal cell and hepatocellular carcinoma, soft tissue sarcoma, GIST tumors, mesothelioma, and carcinoma of the appendix. There is also evidence of activity in hematological malignancies, especially multiple myeloma. Disease stabilization, defined as time on treatment without progression for at least 6 months has been seen in 20 tumor types, including metastatic renal cell cancer, hepatocellular carcinoma, melanoma, carcinoid, prostate, head and neck, breast, and small cell lung cancer. Responding patients, including stable disease, have been treated for various durations up to more than three years.
KRX-0401 (perifosine) is in-licensed by Keryx from Aeterna Zentaris, Inc. (AEZS:AEterna Zentaris Inc.
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Last: 0.590.00-0.02%
3:59pm 11/07/2008
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AEZS 0.59, 0.00, 0.0%) (CA:AEZ: news, chart, profile) in the United States, Canada and Mexico.
About Keryx Biopharmaceuticals, Inc.
Keryx Biopharmaceuticals is focused on the acquisition, development and commercialization of medically important, novel pharmaceutical products for the treatment of life-threatening diseases, including renal disease and cancer. Keryx is developing Zerenex(TM) (ferric citrate), an oral, iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. Zerenex is currently in Phase 2 clinical development for the treatment of hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease. The Company is also developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that modulates Akt, a protein in the body associated with tumor survival and growth. KRX-0401 also modulates a number of other key signal transduction pathways, including the JNK and MAPK pathways, which are pathways associated with programmed cell death, cell growth, cell differentiation and cell survival. KRX-0401 is currently in Phase 2 clinical development for multiple tumor types. The Company also has an in-licensing and acquisition program designed to identify and acquire additional drug candidates. Keryx is headquartered in New York City.
Cautionary Statement
Some of the statements included in this press release, particularly those anticipating future clinical and business prospects for KRX-0401, may be forward-looking statements that involve a number of risks and uncertainties. For those statements, we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. Among the factors that could cause our actual results to differ materially are the following: our ability to successfully complete clinical trials for KRX-0401; our ability to meet anticipated development timelines for KRX-0401 due to recruitment, clinical trial results, manufacturing capabilities or other factors; and other risk factors identified from time to time in our reports filed with the Securities and Exchange Commission. Any forward-looking statements set forth in this press release speak only as of the date of this press release. We do not intend to update any of these forward-looking statements to reflect events or circumstances that occur after the date hereof. This press release and prior releases are available at http://www.keryx.com. The information in our website and in the American Society of Hematology's website is not incorporated by reference into this press release and is included as an inactive textual reference only.
KERYX CONTACT:
Lauren Fischer
Director - Investor Relations
Keryx Biopharmaceuticals, Inc.
Tel: 212.531.5965
E-mail: lfischer@keryx.com
SOURCE Keryx Biopharmaceuticals, Inc.
http://www.hematology.org
Copyright (C) 2008 PR Newswire. All rights reserved
nice shake by the MM's
QI has potential too
KERX just hit .33
44% today! Dont miss this one
QI, KERX - GOOD POSSIBILITIES
KERX - QI Watchem! QI over a 1.00 last month now 17 cents
QI will make HUGE gains with volume
In QI at .18
this is encouraging news on KERX if the CEO is buying!
2nd day of the run, I bought in at .37 sold at .47
then later that day rolled it back in at .41
watched it go down the next day to 22 cents, then bought more at 24 cents....it took 20 minutes to get the buy order filled,,,wonder why? short squeeze perhaps?
'Threeflight' where did you find this information on KERX?
KERX>the ceo bought 150 K at .41 2 months ago. So lets use that as our new base on our way to .80 and beyond.