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Article just out "Biotechs with Ground-Breaking Potential
Anavex Life Sciences (AVXL) stock popped nearly 30% after presenting some encouraging results from one of its Alzheimer's candidates. It's not uncommon for promising Alzheimer's results to move a stock. What makes the recent climb in Anavex shares so interesting is that it occurred in response to preclinical data observed in rats, from a drug that flies in the face of the prevailing thesis of how the disease could be treated. Anavex Life Sciences Corp. (AVXL) is dedicated to the development of novel drug candidates to treat central nervous system (CNS) diseases and various types of cancer. Anavex's lead drug candidates, ANAVEX 2-73 and ANAVEX PLUS, the combination of ANAVEX 2-73 and donepezil (Aricept(R)), are currently in a Phase 2a clinical trial for Alzheimer's disease. The drug combination ANAVEX PLUS produced up to 80% greater reversal of memory loss in Alzheimer's disease models versus when the drugs were used individually. ANAVEX 2-73 is an orally available drug candidate that targets sigma-1 and muscarinic receptors and successfully completed Phase 1 with a clean data profile. Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer's disease.
By mid August they could have been fully enrolled.
MACD is about to flip which usually comes before a price jump.
Well we're down below 6 now so people do believe him
What's the problem - is Missling making it difficult for you to make money shorting this stock? Perhaps you should just cover on Monday morning.
On Sept 28, Anavex announced that patient "enrollment" for Phase 2a had been completed, which implies the last patients to enroll would not have completed 2a until mid-to-late Oct, which is consistent with your observation. Thanks for keeping us accurate.
Anavex Life Sciences Corp. (“Anavex” or the “Company”) (OTCQX: AVXL), a clinical-stage biopharmaceutical company developing drug candidates to treat Alzheimer’s disease, other central nervous system (CNS) diseases, pain, and various types of cancer, today announced that patient enrollment for the Phase 2a clinical trial of ANAVEX 2-73 has been completed ahead of schedule.
He's referring to AMBS. They're tied to the AVXL P2 trial.
Exit positions before Thanksgiving weekend?
Time to move on to other stocks?
PRs like this two days in a row is not Missling's style.
This morning may be front running the news of a BP partner any day now. So if partner for Epilepsy people will not scratch head.
After hours thought: wonder if a lot of the shorts in KBIO were also in avxl (and others). When kbio went up 400% in minutes, many accounts went negative impact, and brokers forced them to cover their other positions.
Uh...I think your chart is upside down.
This has been stated by Missling several times. The 50 mill with LPC will not cover PIII expenses
138000 shares pre market and it's up 30 percent finally a green opening :)). The question now is what's gonna happen when it opens??
I have not seen him state that Anavex will partner before phase 3
It will be designed as a pivotal trial, meaning that if results are good the trial could be sufficient for FDA approval.
I thought I saw somewhere that Dr. Missling had a connection with Pfizer. Does anyone recall the connection?
Here's what I found interesting in the article:
"Other big pharma companies like Biogen (NASDAQ:BIIB) and Eli Lilly (NYSE:LLY) have been struggling with their Alzheimer's research. Biogen saw a setback with its Alzheimer's drug in the phase 1b trial, known as the PRIME trial. This is because the company saw good results using its 3 mg and 10 mg of its drug, but failed to produce similar results in the 6 mg dose cohort. The drug was shown to reduce amyloid plaques in the brain but had no effect on cognition like Anavex did. Eli Lily saw some good preliminary results, but they tested their trials by comparison. That means they took one of their phase 3 trials and compared it with the other. They looked at patients who took treatment early compared to those that took treatment afterwards. If you want to pick a winner in the Alzheimer's space then Anavex is your best bet based off statistical results to date."
LOL - yeah, I was expecting another bash but instead got a pump. Even some of the shorts (the smarter ones) are now signaling that it's time to buy now.
Think about it... It has to be the algos.
Thanks for making me laugh, shorty!
I agree that it's not fully accurate and doesn't show everything, but from what's been reported, it shows a huge drop in shorting since Nov 10.
A TON of junk on this board over night.
Shorty is scared.
Huge hedge funds will short this as low as they want
This can still go way lower and you dont have to cover to short more you must be knew to investing
If the shorts were in control, we wouldn't have seen green all day. Perhaps you should go back to making more of your laughable charts.
I think today trading was the first sign of bottoming
Low volume and trading most of the day at the high
Until he (Dr. Missling) does go on the offense against these shorts reports and bashers, this pps will only continue to drop.
Seems as if this venue was made for short sellers
they are paid to keep shareholders happy happy happy smile
I'd rather not say because I don't like giving advice as to a price for when to buy or sell. I have a considerable number of shares as do many others on this board - started buying last April when it was $.27-28 pre-split. I still have ALL of my shares and will NOT sell them anytime soon. I've traded many stocks, but not this one - there's way too much upside to remaining long and patient. And given this stock's history and Dr. Missling, I know the unexpected can happen at any time - very MUCH volatility and upside potential to be trading and left out in the cold when this jumps. I've seen this happen too many times to many traders on this board. One day they're pumping it and the next day they're bashing it.
actually 13 million
It's a preposterous soft bash. That would be $0.25 pre-split. Heck, the asset value of the office furniture is higher than that. :)
Thanks Tom - if I'm reading this correctly, Friday's shorting shares are less than 20% of last Tuesday's amount of 1.6m. I suspect today's is even less than Friday's. This indicates the majority of the shorts have left with a few stragglers left behind or just haven't covered yet.
AVXL has closed higher every month this year, EVERY MONTH so far
Tom, we can agree to disagree, but the fact that the bulls were in control most of the day is something that I find VERY encouraging! Not something we've seen for several days - they're starting to get momentum! If the shorts were in control - why would they wait until the end of the day to throw everything but the kitchen sink? They can only push this down so far.
This end of day dump by the sellers... such a manipulation game. still going on....
seeking breakthrough designation "upon completion of 2A."
"Do we have any hope?"