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Monday, 12/14/2015 10:31:16 AM

Monday, December 14, 2015 10:31:16 AM

Post# of 463743
Article just out "Biotechs with Ground-Breaking Potential

Anavex Life Sciences (AVXL) stock popped nearly 30% after presenting some encouraging results from one of its Alzheimer's candidates. It's not uncommon for promising Alzheimer's results to move a stock. What makes the recent climb in Anavex shares so interesting is that it occurred in response to preclinical data observed in rats, from a drug that flies in the face of the prevailing thesis of how the disease could be treated. Anavex Life Sciences Corp. (AVXL) is dedicated to the development of novel drug candidates to treat central nervous system (CNS) diseases and various types of cancer. Anavex's lead drug candidates, ANAVEX 2-73 and ANAVEX PLUS, the combination of ANAVEX 2-73 and donepezil (Aricept(R)), are currently in a Phase 2a clinical trial for Alzheimer's disease. The drug combination ANAVEX PLUS produced up to 80% greater reversal of memory loss in Alzheimer's disease models versus when the drugs were used individually. ANAVEX 2-73 is an orally available drug candidate that targets sigma-1 and muscarinic receptors and successfully completed Phase 1 with a clean data profile. Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer's disease.

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