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There is no hill or mountain we can’t climb
Babe
Agree that UK approval is the earliest and will serve as lever and to keep fda honest. EMA will follow UK.
Nwbo will apply for UK approval as soon as MIA approved, which is any day now. All the prep LP described is to enlighten shareholders who are understandably frustrated at the passage of time. I don’t believe it was meant to imply UK approval filing will be delayed, as the work has been in progress earlier.
FDA filing might be later, but that has been my assumption.
In any event, first approval is the current goal and it is being focused on and worked.
The negative narratives are going to be blaring out louder and louder until approvals and beyond, because that’s what they’re being paid to post imo.
I’ll be picking up your shares if you give them up at a opportune price!
Obviously another orchestrated move on the stock price since longs would not sell on the basis of what was shared at the ASM.
I was not at all disappointed by what LP shared, and she sounded upbeat and confident, and honest to me.
She confirmed a lot and she gave insights, and she didn’t just barrel through the Q&A.
Let’s not forget we have boots on the ground at the event and they have further opportunity to interact with LP and other company reps and probably share bonus insights with us!
My mom passed from cancer early Thanksgiving morning 2019, and we miss her every holiday since, but nobody gets out alive as they say… despite requesting that her tumor, or a piece, be stored properly for a remote chance at DCVax, it was stored in the usual paraffin. I wanted that potential treatment to be a possibility, even if extremely remote, as her cancer was inoperable and metastasized.
Btw, I highly recommend Dr Roger Hartl of Cornell Weill for spinal surgery and treatment.
We can use all the ethereal positive energy we can get!
Thanks Doc, appreciate the background. I lived through it myself but my recall is not at past peak level.
I’m interested in your anti aging regimen!
I drink a glass of red wine per day and started taking 100mg pycnogenol. I know the glass of wine doesn’t provide anywhere near the resveritol (sp?) but it reduces my stress in general
And I heard from my sauce, that there are going to be some spicy meatballs!
Oh, source, never mind
That’s a pretty nice image!
Add the full seats at family holiday get togethers that would likely be empty!
Tuesday?
That logic may still be valid, however since 2010 a number of different or new factors and developments have arisen.
For one, did anyone know in 2010 that combo treatments would hold such humongous efficacy as the current preview indicates!
Being repetitive, I trust LP and company to keep shareholders interest prominently in mind, next only to the interests of the patients and the fight against cancer.
UK MAA my friend!
Only half joking, but you mean in addition to the halt at market close ?
Thanks for the dd!
Nwbo also holds a great many patents for DCVax and DCVax combinations !
Congratulations!!!!
Oligarchs suddenly seem to be tripping and falling or committing suicide in an unusually large number of cases, and it’s just a wild coincidence, hmmmmm.
Who the heck do you think you are and where do you get off thinking you’re better than anyone else here or anywhere?
That’s ok I wouldn’t want to hang around with you either based on your statement.
That must be Ray Donovan’s whicked smaht dendritic cell from south Bahston Mass.
You’re right, no more sugar, no more daddy!
Like Margo Robbie’s character said in the Wolf of Wall Street
If you worked on DCVax you could make the FlaskWorks based process fly-by-wire
We guys sure got the short stick when it comes to the happy wife happy life advice.
We get the Happy Hubby Who Cares treatment or usually no treatment at all
Then everyone wonders why older gentleman wind up leaving for the stereotypical younger woman (they haven’t learned to ignore us yet )
Of course the above is completely hypothetical !
Great reference but geesh, breakthrough GBM vaccine at 17th place versus hedgehog in the top 10 !
Maybe we need a cute image for the vaccine, like Murci the whacky dendritic cell
Also reasonable thinking and not a bad outcome for patients and investors
Reasonable thinking and not a bad outcome for patients and investors
Let me simplify the message and sales pitch for murcidencel -
Murcidencel is the only breakthrough in the treatment of GBM in more than 20 years, and the only known treatment with a significant survival tail, which is hope for long term survival and cure.
Murcidencel is the only option for rGBM
Combination of Murcidencel with CI such as Keytruda shows very promising interim results pointing to possible >55% cure rate.
Any questions?
All the above is unprofessional opinion only, I am not a physician nor do I play one on TV. Anyone facing a GBM diagnosis should work with their medical team and neurologist, and I’d recommend Dr Liau, Dr Ashkan, and the other top neurosurgeons who took part in the DCVax L phase 3 trial!
Oh btw, the market was down across the board yesterday and nwbo was fractionally higher…. Since you’re exaggerating a wee bit imo
Look again, then look again, rinse and repeat since the sp is just meandering a fraction of a cent around zero change.
And it only takes a first partner/licensee to get the snow ball rolling! Of course we need an approval to allow sales.
Although obvious (maybe I’m a distant relative of Captain Obvious) -
Clearing out the noggin of the noise, if dcvax enables CI from Merck, BMS, Astrog, JNJ, etc., to become efficacious for indications that they otherwise have not been, then wouldn’t nwbo be in a better position partnering or licensing DCVax with each of these BPs?
Conversely, agreeing to a BO to any one BP, while advantageous to that BP, may or may not strengthen the DCVax position and in the worst case expose DCVax to delay and/or bury tactics and challenges from the BPs left out of the deal.
So, by keeping a centralized ownership and partnering and/or licensing DCVax the centralized owner (nwbo or derivative entity) ensures DCVax gets appropriate ongoing support, gets maximized multiple revenue streams, gets partners to ante up trial, development, and commercialization, and the nwbo/survivor entity has the most control over directions and decisions for the future of DCVax. Also may maximize penetration to as many patients worldwide as possible.
Again, this can look like the Coca Cola - Bottlers model, however the large BPs may have a lot more clout than a Coke bottler.
Bidah, bidah, bidah, that’s all folks
Just scanned the board, and it looks like the negative narratives mercenaries are out in force.
Suppose it’s because of the ASM and vote tomorrow?
Yes, that was an interesting and effective idea by whomever was responsible for coming up with that particular representation of being forcefully escorted to eternal damnation!
That’s where we see things differently.
I never felt the company and trial were rudderless, just that only so much of the plan was going to be publicly revealed and much of the time would be in radio silence.
One must also accept that in undertaking any large and lengthy project, some things change for a variety of reasons.
I also felt and accepted that LP was and still is on a mission to bring DCVax to treat cancer as of the utmost importance. Anything and anyone could be collateral damage in com0leting the mission, including shareholders if necessary.
That said, I think LP had to dangle carrots in front of us along the way in order to survive, however I think LP has avoided selling out the shareholders, especially in the last few years.
In summary, I trust LP to be doing the best job she can, and I doubt there are many who could have done better with what she had to work with and against multiple big bad wolves!
So I try to pass the time to blast off as chill as possible and not second guessing and backseat driving too much.
GLTA
It’s possible in an adversarial and manipulated environment.
NWBO brought a law suit against the big dogs alleging spoof trading practices to manipulate the share price.
In such an environment, nwbo is focusing on getting each of the necessary milestones done, focusing on bringing the goods to achieve approvals.
This hasn’t been a cake walk and success is never guaranteed until approvals are granted and sometimes not even then, as in the case of Provence.
I believe LP and I believe LL, and in constantly reviewing the due diligence, and I remain fully invested!
I could be wrong, and it wouldn’t be the first or second time, however imo the risk reward is worth it to me, especially as the step by step progress has been made.
But you have to assess for yourself, and decide how much risk you is appropriate for your circumstances.
Good luck
I was challenged to come up with lyrics to And so this is Christmas by John Lennon.
Another poster knocked that challenge out of the park with brilliant lyrics, but I had to complete the challenge nonetheless.
It’s no wonder I didn’t have a career in songwriting, or comedy for that matter, but it keeps me off the streets and out of trouble
On that point we agree!
The next 3 months should tell the tale of success or failure or something in between!
Did you hear that? Beam me up Scotty!
I bet they’re not named Clarence, and we won’t hear the ringing bells of angels earning they’re wings!
I wonder what you hear when the dark angels earn their horns? Maybe FUD?
Only if us longs are singing the blues, which we’re not, and if we were singing blues we’d be right about at the happy chord resolution transition.
Like Jimi sang, “if my baby don’t want me no more, I know her sister will “ (upbeat finish)
Sssshhhhhhhhh…..
Be vwery, vwery quiet….
I’m hunting bunny whabbit!